Lecure 24

Question 1

myeloid

Answer 1

pre programmed
phagocyte and macrophage

Question 2

lymphoid

Answer 2

b and t

Question 3

fab

Answer 3

bind to antigen
-selective

Question 4

genes on antigene are made of

Answer 4

VDJ
-1 loci for H 2 for L

Question 5

b cells have

Answer 5

2 alleles that one silence

Question 6

once b cell makes

Answer 6

one antibody
-mature in spleen

Question 7

RAG 1 and 2

Answer 7

do genome editing
-look like transposome

Question 8

CDR

Answer 8

highly variable loop
-contacts antigen
-highly variable and mutate in junction

Question 9

what does a foreign antigen trigger

Answer 9

affinity maturation then class switch

Question 10

what triggers B cell active and recomb

Answer 10

cytidine deanimase (AID) is the enzyme that activates to VDJ recombination

Question 11

class switch

Answer 11

go to specific locations
m to g to e or a

Question 12

avoid immune rxn w monoclonal antibodies with

Answer 12

phage display

Question 13

mhc 1

Answer 13

present antigen

Question 14

T secrete?

Answer 14

cytokines to trigger class switch and hypermutation

Question 15

beta subunit of mhc 1 example of

Answer 15

codominance

Question 16

mhc2

Answer 16

show exogenous to cd4/ helper

Question 17

halotype

Answer 17

mhc 1 combo
chromosome 6

Question 18

mhc

Answer 18

fits specific side chains and are given to children

Question 19

devil face tumor

Answer 19

inactive mhc so k t doent kill `

Question 20

muchos typos de cancer

Answer 20

no tienen mhc para detectar

Question 21

algunos canceres hacen

Answer 21

PDL1 para no aparecerse a los t

Question 22

keytruda

Answer 22

anti pdl1 so t cells can kill cancer

Question 23

chimeric antigen receptors on t cells

Answer 23

find cancer through given protein sequence, active t cell for a response