Lectures 6-8 Flashcards
What are the three types of chromosomal mutations?
- Loss of genetic material
- Gain of genetic material
- Relocation of genetic material
What abnormal event during meiosis results in missing/extra chromosomes in gametes?
Nondisjunction.
If inversion of genetic material involves the centromere, it is…
Pericentric.
Translocation is the swapping of genetic material between homologous chromosomes. True or false?
False.
If inversion of genetic material doesn’t involve the centromere, it is…
Paracentric
What will the four gametes be if nondisjunction occurs during meiosis I?
n+1, n+1, n-1, n-1
What will the four gametes be if nondisjunction occurs during meiosis II?
n, n, n+1, n-1
The Oxford Nanopore is portable. True or false?
True.
Illumina sequencing takes a few days. True or false?
True.
What do we call a series of overlapping sequences used to reconstruct the original sequence?
A contig.
A reconstructed portion of the genome, made of contigs + gaps, is called:
A scaffold.
De novo sequencing is…
Sequencing without a reference genome.
What are three areas that genomics can be used in?
- Phylogenetics
- Genome biology/evolution
- Personalised medicine
Epigenetics is:
Changes in gene expression without DNA change.
Is DNA ever naked in vivo?
No.
