Lectures 10-12 Flashcards

1
Q

what’s N.O.G (3 types of nervous system cells)

A

Neurons
Other cells
Glia cells

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2
Q

How many neurons are in the human body and what do neurons represent

A

100,000,000,000 in human body (triple 3’s)

Main signaling units in Nervous sytem

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3
Q

What 3 types of cells fall under Other cells?

A

endothelial cells
ependymal cells
micro glia

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4
Q

How many Glial cells do humans have and how many kinds of glial cells are in this category ?

A

100,000,000,000,000 (quadruple 4’s) and 7 types of glial cells are in this category

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5
Q

How are neurons utilized in Nervous system? (the star actor)

A

interconnections enable everything from basic reflexes to cognitive function

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6
Q

What are the double r’s for neurons , what can they not do ?

A

Replicate
replace
Cannot be replicated or replaced once gone

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7
Q

what are “other cells” utilized for in Nervous system? (Co star)

A

Variety of important supporting roles

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8
Q

What are Glia cells utilized for in Nervous system? (Co star)

A

Plays primarily supporting role

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9
Q

How do neurons communicate ?

A

Neuron sends , processes and receives signals then stores information as well

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10
Q

How do neurons communicate? PSA and 1)… 2)… processes

A

Combo of electrical and chemical processes as well as Post synaptic signaling, Synaptic transmission and Action potential

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11
Q

Neurons structure typically has ……. cellular characteristics

A

Eukaryotic

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12
Q

what are the cellular characteristics? NPC

A

Nucleas
Plasmalemma
Cytoplasm

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13
Q

what’s inside cytoplasm?
(2)

A

Cytosol
Cyto skeleton

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14
Q

What’s inside membrane organelles? REP

A

Endoplasmic reticulum
Ribosomes
Polysomes

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15
Q

4 distinct cellular characteristics of a neuron ( 4 parts of an Axon) SADS

A

Shape: cell body (soma)
Axon
Dendrites
Synapse

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16
Q

what function do axons have?
Hint: theres someone on trains who gives the go for everything

A

Conduct action potentials and transmit synaptic signals

17
Q

4 Parts of method to an Axon
in in on out

A

Input
integration
Conduct
Output

18
Q

Morphological Characteristics of Axon(4)

A

1 or more axon per neuron

Varys in length but remains constant

1 or more pre and post synaptic specializations

No myelin

19
Q

3 Cellular characteristics of Axons (SAD) and what do they do

A

Synapses: communication point between 2 neurons
axon: axon hillock and myelination
dendrites : receive and integrate synaptic signals

20
Q

3 functional neuron classes (SIM)

A

sensory
interneuron
motor

21
Q

3 structural neuron classes (the polar bears) One two many…

A

Uni polar-1
Bi polar-2
Multi polar-many

22
Q

3 Types of Glia cells (MAM) and what other cells relate to those 3 groups ?

A

Myelinating Glia- schwann cells
Astroglia- Radial glia
Micro glia

23
Q

what is myelinating glia ? (the big hug)

A

At Glia cell membrane, myelins produced and wraps around axins

24
Q

2 Functions of myelinating Glia (AS)

A

Action potential conduction
Structural support

25
Clinical importance of Myelinating Glia (2)
Type 1A tooth disease peripheral myelin protein
26
Astroglia 3 functions
compartmentalizations and physical support for neurons Regulates chemicals in extra cellular space Supports formation of BBB
27
definition of Radial glia and it’s function
It’s a young astroglia To guide neuronal migration during development and to mature into an astroglia
28
What happens to Micro glia throughout development
Numerous and active during development, numerous and inactive in adulthood
29
What are the immune cells called and what group do they belong to? phag
Phagocytose debrese found in Microglia group
30
Where are ependymal cells and endothelial cells located?
ependymal: cerebroventricular system endothelial: blood vessel walls, BBB
31
why do we need blood brain barrier (BBB) but not barrier in liver or kidney?(4)
functional importance brains disproportionate exposure to blood heavy reliance on chemical communication Limited ability for brain repairs
32
How is blood brain barrier achieved? think roads and when they’re busy
Endothelial cells (main star) routes are reduced -resulting in tight junctions tight junctions
33
What is able to get through blood brain barrier? (4)
Small uncharged molecules Actively transported Lipid soluble Water soluble
34
What is not able to get through blood brain barrier
Big things/cells Large polar molecules charged molecules
35
Clinical importance of Blood brain barrier
Breakdown of barrier could play a role in Nervous system disorders and is a critical consideration when designing brain drugs
36
Blood brain barrier: Disorders helped or seen changes in: Remember Bath’ em
Brain tumours alzheimer’s trauma brain injury hypertension epilepsy Multiple sclerosis