Lecture7: Viral Structure And Classification Flashcards

1
Q

What are viruses diameter

A

20-400nm

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2
Q

What covers the nucleocapsid?

A

Matrix protein

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3
Q

What does the matrix protein do?

A

Serves as a bridge for the envelope

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4
Q

What are viruses lacking envelope called?

A

Naked viruses

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5
Q

Which virus type contains two identical copies of its genome?

A

Retroviruses such as HIV

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6
Q

What are enveloped viruses liable for?

A

Destruction via heat, ethanol, detergents

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7
Q

What are defective viruses?

A

Viruses that lack a complete genome, thus can’t replicate

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8
Q

What are Satellite Viruses?

A

A type of defective viruses, only capable of replication when a helper virus is present

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9
Q

Name a Satellite Virus

A

Hepatitis D

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10
Q

What virus type is liable for heat damage?

A

Enveloped viruses

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11
Q

What pH is the stable value for viruses?

A

5-9

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12
Q

What pH destroys all viruses?

A

Alkaline

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13
Q

What is the best-in-class virus purification method?

A

Formaldehyde

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14
Q

What are alcohols ineffective against?

A

Picornaviruses

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15
Q

What’s a bacteriophage?

A

A virus-eating bacteria

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16
Q

When a phage is integrated into a bacterial genome it’s called a..?

A

Prophage

17
Q

What do the tails of a phage do?

A

Inject nucleic acid into a host cell

18
Q

What are Lytic Phages

A

They kill their host cells

19
Q

What state do Temperate phages enter?

A

Nonlytic prophage state

20
Q

Name a temperate phage

A

E.coli phage

21
Q

Why phage therapy?

A

Strong host specificity, and new infectivity, meaning they don’t get resistant like antibiotic immunity and no collateral damage, very accurate

22
Q

What is a complete virus particle called?

A

Virion