Lecture7: Viral Structure And Classification Flashcards
What are viruses diameter
20-400nm
What covers the nucleocapsid?
Matrix protein
What does the matrix protein do?
Serves as a bridge for the envelope
What are viruses lacking envelope called?
Naked viruses
Which virus type contains two identical copies of its genome?
Retroviruses such as HIV
What are enveloped viruses liable for?
Destruction via heat, ethanol, detergents
What are defective viruses?
Viruses that lack a complete genome, thus can’t replicate
What are Satellite Viruses?
A type of defective viruses, only capable of replication when a helper virus is present
Name a Satellite Virus
Hepatitis D
What virus type is liable for heat damage?
Enveloped viruses
What pH is the stable value for viruses?
5-9
What pH destroys all viruses?
Alkaline
What is the best-in-class virus purification method?
Formaldehyde
What are alcohols ineffective against?
Picornaviruses
What’s a bacteriophage?
A virus-eating bacteria
When a phage is integrated into a bacterial genome it’s called a..?
Prophage
What do the tails of a phage do?
Inject nucleic acid into a host cell
What are Lytic Phages
They kill their host cells
What state do Temperate phages enter?
Nonlytic prophage state
Name a temperate phage
E.coli phage
Why phage therapy?
Strong host specificity, and new infectivity, meaning they don’t get resistant like antibiotic immunity and no collateral damage, very accurate
What is a complete virus particle called?
Virion
