Lecture Exam 3 Flashcards
Immunity
Providing resistance to disease.
The innate system is specific or nonspecific?
Nonspecific
The adaptive system is specific or nonspecific?
Specific
Pathogen
Harmful or disease causing micro-organisms.
Surface Innate Defensive Barriers
Skin, Mucous Membranes
Surface Barrier Protection:
Physical barrier, chemicals secreted
Internal Innate Defensive Barriers, Cells and Chemicals:
Phagocytes, Natural Killer Cells, Antimicrobial Proteins, Inflammatory Response, Fever
Neutrophils
Most abundant phagocytes, become phagocytic on exposure to infectious material.
Macrophages
Develop from monocytes, chief phagocytic cells.
Steps of Phagocytosis
Phagocyte adheres, Phagocyte forms, Lysosome fuses, Lysosome digests, Exocytosis
Natural Killer Cells
Nonphagocytic large granular lymphocytes, Attack cells that lack ‘self’ cell surface receptors.
Apoptosis
Programmed cell death
Inflammatory Response
Prevents spread of damaging agents, disposes of cell debris, alerts adaptive immune system, sets the stage for repair.
Hyperemia
Vasodilation of local arterioles that causes redness and heat.
Exudate
Fluid filling clotting factors and antibodies.