Lecture 9- complex brain functions Flashcards
what is the normal 24 hour sleep/awake function cycle
2/3 awake
1/3 sleep
what structure helps the circadian rhythm with wakefulness
brainstem
ARAS
what structure helps the circadian rhythm with sleep
thalamus
how does the thalamocortical neurons help with sleep
low frequency action potentials with Ca2 spike
how does the thalamocortical neurons help with awake
high frequency action potentials without Ca2 spike
what are the nuclei and corresponding neurotransmitters that help the ARAs with alertness
cholinergic: acetylocholine (both ascending and descending tracts)
raphe nuclei: serotonin
locus coeruleus: norepinephrine
what structure has the final say in circadian rhythm
hypothalamus
what does the lateral nucleus of the hypothalamus do for the circadian rhythm
improve alertness of higher cortical and subcortical structures
activate ARAS- alertness
activate tuberomammillary- arousal
what does the tuberomammillary nucleus of the hypothalamus do for the circadian rhythm
awake
histamine
increase arousal for CNS
what does the VLPO nucleus of the hypothalamus do for the circadian rhythm
asleep
inhibit ARAS and tuberomammillary nucleus
decrease alertness and arousal
what structures are apart of DMN
post cingulate cortex
ventromedial pre frontal cortex
temporal parietal junction
what structure is most active at cognitive rest
posterior cingulate cortex
what functions does DMN play a role in
social cognition- know thyself (DMN) know others (all others)
social life
what are the 4 phases of attention
selection
sustenance
division
change
what is the role of the subcortical regions in attention control network
reflexive
what are the subcortical structures used for attention
superior colliculus to coordinate locomotion (MLR)
thalamus- pulvinar nucleus- dorsal stream (DLR)