Lecture 9 Flashcards

0
Q

Explain time dependency for neural systems and there two periods.

A

If neural signals are not used then they will break done and became unavailable for use. There is a critical period where if the neural signals aren’t used in this period the function will be lost and there is a sensitive period where the function may still be apparent but it won’t be as good as it could have been

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1
Q

What two things is the maintenance and reorganisation of neural systems dependent upon?

A
  1. Time dependency

2. Experience/use

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2
Q

Explain experience/use in the maintenance and reorganisation of neural systems. What did hebb state?

A

If neural signals aren’t used then there synapses are weakened. As hebb says, “neurons that fire together, wire together”

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3
Q

Explain what the experiments on deprivation, enrichment and exercise find on both neural structures and behaviour.

A

Experiments found that when an animal is in an enriched environment and performing exercise they have more complex neural structures and are more aware of their environments then those who were deprived.

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4
Q

Where are the greater number of synapses and dendrite spines found?

A

In the dentate gyrus of the hippocampus and olfactory bulbs

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5
Q

What did hubel and wiesels study conclude? What does this support?

A

Hubel and wiesels study found that when you sutured shut an eye in a kitten, neural functioning of that eye was lost. But when a 12 month old cat had it’s eye sutured, there were no changes in ocular dominance but neural signal activity decreased overall. This supports the time dependency and use paradigms for neural system maintenance.

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6
Q

If you look at the layers of the primary visual cortex for a short deprived and long deprived cat, what would you find?

A

That there are no neural structure differences in the primary visual cortex between short and long deprivation of eye sight.

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7
Q

Explain competition in neural development both in terms of visual and motor processes.

A

Competition in neural development occurs when a function is reduced (e.g. Seeing from one eye) and the opposite function is increased. So neurons for extinct functions would decrease and neurons for opposite functions would increase. It’s a shift and rebalance of multiple processes.

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8
Q

Explain the effects of knudisens and brainless barn owl experiment on sensory cortex maps.

A

Knudisens and brainards experiment on barn owls found that when owls were fitted with vision altering eye prisms they struggled to locate prey visually and aurally. However, with practice they could locate the prey as the vision and auditory cortex maps shifted the corresponding amount to alter for real space differences.

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9
Q

In what layer of the primary visual cortex would you find the activation of neural signals ?

A

Layer IV. Or 4.

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10
Q

Where in the auditory system would the auditory map shift to accommodate changes?

A

The tectum

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11
Q

Explain the relationship between musicality and age.

A

The younger a person is exposed to and practices music the larger the cortical area would be for that function

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12
Q

Does plasticity occur in adults?

A

Yes, to a degree training can induce changes in the cortex to accommodate to new functions

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13
Q

What’s the phantom limb phenomena?

A

The phantom limb phenomena is when you can still “feel” sensations from the limb as though it occurs space.

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14
Q

What did ramachandran discover? Explain why this could happen?

A

When a patient who was missing their left arm after an accident had their cheek stroked they would report feeling in left arm. This could happen because sensations for hands and the faces are adjacently represented on the cortical map therefore the face region would occur more of the hand region now.

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15
Q

What is anterograde neural degeneration?

A

Forward disruption- When the neuron is destroyed from the point of disruption to the synaptic terminals.

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16
Q

What is retrograde degeneration of neurons?

A

Backward disruption- when the point of disruption is from the damaged area back to the cell body.

17
Q

What is transneural degeneration?

A

When there is damage to linked neurons. Both anterograde and retrograde degeneration

18
Q

What is a concussions and what some short term and long term effects?

A

A concussion is when a blow to the head is obtained and there is brief or no loss of consciousness. Short term symptoms include loss of consciousness, temporary confusion, dizziness. Long term symptoms may include internal bleeding, linear or rotational forces to brain stem, behavioural and cognitive problems

19
Q

What is a closed head injury?

A

Force to skull that doesn’t penetrate skull

20
Q

Explain contusions, coupe and contracoup contusions and how they occur.

A

Contusions are the bruising of the brain when it slams against the skull in closed head blows. The coup contusion is the primary blow or impact sight and the contracoup is the secondary impact of the brain slam against the skull

21
Q

What is a haematoma? And what would the consequences be if one was obtained whilst drinking alcohol?

A

When blood vessels are broken or sheared. Alcohol is an anti-coagulant so it thins the blood therefore if a blood vessel is ruptured, the bleeding may not stop/clot as a result of the thin blood.

22
Q

What is an oedema?

A

An oedema forms when the brain swells (usually to form protective cushion) and the pressure is too much for the brain so brain bruises.

23
Q

Explain why epilepsy can occur after brain damage.

A

Epilepsy can occur after brain damage due to scar tissue and the neural structures can be altered

24
Q

What is a penetrating head injury and what are some symptoms?

A

Penetrating head injury is when a blow ruptures the skull. Some symptoms include: bleeding, infections, epilepsy, oedema

25
Q

Explain the case of phineas gage.

A

Phineas gage is a man who had a piece of metal pierce through his skull and frontal lobe. Because of it, although still alive, he suffered major personality changes and eventually died of epilepsy and infection.

26
Q

What is the scientific term for a stroke?

A

Cerebrovascular accidents.

27
Q

Define a Cerebrovascular accident.

A

A stroke is where there is a sudden disruption in the brains flow of oxygen.

28
Q

What are the two types of stroke and what are they?

A
  1. Haemorrhage- when a blood vessel is broken and there is bleeding into the brain. Generally caused by an aneurysm or weakening of vessel wall
  2. Ischemia- when there is a disruption in blood flow due to thrombus (clotting of blood in situ) or embolus (material blocks flow of blood)
29
Q

What are infracts?

A

Infracts are areas of dead tissue in the brain due to lack of flow of oxygen. Generally occurs after a stroke

30
Q

What is the area called that surrounds infracts that still remains alive, just dysfunctional?

A

Penumbra

31
Q

What is cerebral hypoxia and how does it cause neurons to die?

A

Cerebral hypoxia is the loss of oxygen to a group of cells that need oxygen for their mitochondria to provide the cell was energy to respire. When this oxygen is deprived, the cell dies

32
Q

Explain two important factors of neural regeneration in humans.

A
  1. Neural regeneration is high in early development but decrease with age
  2. PNS and CNS don’t regenerate to the same capacity. PNS- Schwann cells promote growth CNS- oligondrendroglia inhibit growth.
33
Q

How long does the regeneration of a proximal stump take?

A

2/3 days

34
Q

If schwann cells are not damage in a neural break what regeneration is likely to occur?

A

Regeneration of the axon is likely to occur to the correct destination

35
Q

If there is a small and complete break in a neuron incl. Schwann cells, what type of regeneration can occur?

A

The axons are likely to re grow but may not connect to the correct target

36
Q

What type of regeneration happens if a complete and large break occurs in a neuron?

A

The axon is unable to regenerate and axons curl up into a tangle .

37
Q

If an axon degenerates what process could occur to maintain normal functioning?

A

If an axon degenerates adjacent nuerons may join up with the degenerated nueron and take over functioning

38
Q

What is neuro genesis? What period of life does it occur? And what would happen if brain damage occurred then?

A

Neurogensis is the period where neurons are produced in the brain. It occurs during the first 18 months of life and if brain damage occurs here then recovery from brain damage is possible

39
Q

What is neural migration? When does it occur? And if damage occurred during this period what would happen?

A

Neural migration is when nuerons join and connect for particular functions. It happens doing the lady trimester and at birth. If damage occurs here then it is hard to recover from

40
Q

Explain what intelligence, sex, age, handedness and personality is suitable to maximise recovery after brain damage?

A

Smart people (due to more synapse), females (due to less lateralisation), left handers (due to less lateralisation), younger the better and a bubbly, extroverted personality ( confound: is it because these people would trust professionals and seek treatment?)