Lecture 9 Flashcards

1
Q

What does the ending -ase usually mean?

A

it is an enzyme

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2
Q

Enzyme’s main way to make reactions happen faster

A

lower activation energy

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3
Q

Explain enzyme’s role in oxygen radicals in the body

A

oxygen radicals are extremely reactive and harmful
enzymes can break down these radicals fast

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4
Q

Define activation energy

A

energy you need to put in for a reaction to occur

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5
Q

Define transition state

A

highest synergy point

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6
Q

What happens during transition state?

A

going toward the product is equally likely as not going toward the product

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7
Q

What do enzymes break down the steps into?

A

reaction intermediates

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8
Q

What are enzymes composed of?

A

Subunits

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9
Q

How are enzymes effected by the reactions they are used in?

A

They are unchanged

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10
Q

What bonds do enzymes form with their substrates in their active sites?

A

non-covalent and sometimes transiently covalent

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11
Q

Why are the side chains of the active site close together?

A

Because of the tertiary structure

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12
Q

What happens when denaturation happens?

A

It takes away the tertiary structure

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13
Q

Define prosthetic group

A

extra cofactors that bind to enzymes to assist it
(like iron–not a part of the actual protein)

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14
Q

Enzymes are extremely…

A

Specific

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15
Q

Define competitive inhibition

A

The competition directly binds to the active site of the enzyme

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16
Q

How to overcome competitive inhibition?

A

By increasing the substrate concentration

17
Q

Define allosteric inhibition

A

Binding somewhere else besides the active site inhibits the activity of the active site

18
Q

Through which method does allosteric inhibition work?

A

negative feedback loop

19
Q

Draw an exergonic reaction with these factors: activation energy, free energy change, new reaction due to enzymes, transition state

A

OK

20
Q

Draw

A