Lecture 11: Oxidative Phosphorylation Flashcards

1
Q

Where does oxidative phosphorylation take place?

A

inner membrane

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2
Q

What is the main job of the ETC?

A

cashing in energy stored in previous NADH and FADH2

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3
Q

How many membrane bound protein complexes are there?

A

4( I-IV)

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4
Q

What are the names of the 2 mobile carriers?

A

CoQ and cytochrome C

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5
Q

Why is oxidative phosphorylation aerobic?

A

oxygen is required as final e- acceptor

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6
Q

Which complexes do H+ go through?

A

I, III, IV

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7
Q

What is the structure of ATP synthase like?

A

motor compose of 2 subunits

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8
Q

What is ATP synthase propelled by?

A

movement of H+ ions through the synthase

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9
Q

How is cyanide harmful?

A

It binds to complex IV and blocks electron flow

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10
Q

What is the symptom of cyanide poisoning and why does that happen?

A

fever because body is stuck in glycolysis which releases a lot of heat and is not very efficient.

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11
Q

What is the 1. way if there is not enough O2?

A

use a new electron acceptor
ex. sulfur bacteria use nitrate

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12
Q

What does fermentation do?

A

Keeps glycolysis running in lack of oxygen

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13
Q

What is lactic acid?

A

pyruvate-> lactic acid in muscles

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14
Q

What is ethanol fermentation?

A

pyruvate-> ethanol like in alcohol

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15
Q

Main purpose of fermentation

A

recycle NAD+

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16
Q

What is the positive side to fermentation?

A

It is very fast

17
Q

Define Warburg effect

A

cancer cells release yellow because of lactic acid release

18
Q

Which indicate to inhibit cell resp. pathway?

A

NADH
ATP

19
Q

Which indicate to active cell resp. pathway?

A

NAD+
ADP