Lecture 8.2 - Oncology

Question 1

What kind of mutations result in cancer?

Answer 1

Lack of differentiation, loss of contact inhibition, unregulated growth, cellular immortality

Question 2

Childhood cancer is broken down into two main groups?

Answer 2

Hematological Malignancies
Solid tumors

Question 3

How is leukemia diagnosed?

Answer 3

Bone marrow biopsy

Question 4

What test is always performed when initiating chemotherapy?

Answer 4

Lumbar puncture

Question 5

Why is a CXR performed on a child who may have cancer?

Answer 5

R/O metastases and abnormal changes including mediastinal mass

Question 6

What is the most common form of childhood cancer?

Answer 6

Leukemia

Question 7

What are the two main forms of leukemia?

Answer 7

Acute Lymphoid
Acute Myelogenous

Question 8

What kind of childhood cancer is more common in White boys between the ages of 2-5?

Answer 8

Acute lymphoid

Question 9

What kind of childhood cancer is similarly common in males and females and across ethnicities, and is most common in the first year of life?

Answer 9

Acute Myelogenous

Question 10

How is Hodgkin’s disease diagnosed and treated?

Answer 10

Staged through CT, bone marrow aspirations, X-rays, Lumbar puncture.

Treated with aggressive radiation and chemotherapy.