Lecture 8.1: Parturition Flashcards
What is Labour?
A series of continuous, progressive contractions of the uterus that help the cervix dilate and efface that results in expulsion of products of conception after 24 weeks
When in the pregnancy is it classed as Spontaneous Abortion?
Before 24 weeks
When in the pregnancy is the baby classed as Pre-Term?
Before 37 weeks
When in the pregnancy is the baby classed as Term?
37-42 weeks
When in the pregnancy is the baby classed as Post-Term?
After 42 weeks
How many Stages of Labour are there?
3
What happens in Stage 1 of Labour?
- Interval between the onset of labour and full cervical
dilation - Creation of the birth canal
What are the 2 Phases of Stage 1 of Labour?
- Latent phase: onset of labour with slow cervical
dilation to ~4 cm and variable duration - Active phase: faster rate of cervical change, 1-1.2 cm
/hour, regular uterine contractions
What happens in Stage 2 of Labour?
Delivery of the foetus
What happens in Stage 3 of Labour?
Delivery of the placenta and membranes
Three Ps of Labour
- Powers
- Passenger
- Passage
When is the Dating Scan done? What does it show?
- Approx. 12 weeks
- Confirms dates and identifies singleton or multiple
pregnancy
By what week is the Uterus palpable?
12 weeks
By what week does the Uterus reach the umbilicus?
20 weeks
By what week does the Uterus reach the Xiphisternum?
36 weeks
How to describe baby’s position in uterus towards the end of the pregnancy
- Lie: Longitudinal/Oblique/Transverse
- Presentation: Cephalic/Breech
- Anterior/Posterior
- Occipital/Sacral
How much does cervix dilate in labour?
Up to 10cm
Maximum size of birth canal determined by pelvis, how large is the Pelvic Inlet typically?
- 13.5cm X 11 cm
- Softening of ligaments may increase it
After 36 weeks, the presenting part of the baby..?
“Sinks” into pelvis, known as the “lightening”
Does “lightening” occur in multi-parous women?
- Happens less in multi-parous women
- Multi-parous women often have some painful powerful
contractions a few days before - But not regular and not effective in dilating the cervix
Creation of the Birth Canal
- Expansion of soft tissues
- Lower uterine segment
- Cervix
- Vagina
- Perineum
- Some relaxing of ligaments to increase pelvic inlet,
cavity and outlet
What is ‘cervical ripening’?
The normal process of softening and opening the cervix before labor starts
What processes occur during ‘cervical ripening’?
- Reduction in collagen
- Increase in glycosaminoglycans
- Reduced aggregation of collagen fibres
What triggers ‘cervical ripening’?
- Triggered by prostaglandins
- PGE2 and F2-alpha
What is the structure of the cervix throughout most of the pregnancy?
- Cervix retains foetus for most of pregnancy
- Tough, thick walled 3 cm canal
- Collagen
- Cervical incompetence
What is Cervical Effacement?
Effacement means that the cervix stretches and gets thinner
‘Braxton-Hicks’ Contractions
Also known as prodromal or false labor pains, are contractions of the uterus that typically are not felt until the second or third trimester of the pregnancy, they are the body’s way of preparing for true labor
Uterine contractions have two major goals, what are they?
- To dilate cervix
- To push the foetus through the birth canal
Contractions made more forceful and frequent by…?
- Prostaglandins (more Ca2+ per action potential)
- Oxytocin (more action potentials, lower threshold)
What are Prostaglandins? Where are they mainly produced?
- Biologically active lipids
- Local hormones
- Produced mainly in endometrium
What is production of Prostaglandins controlled by?
Production controlled by oestrogen progesterone ratio
What effect do Prostaglandins have?
- Powerful contractors of smooth muscle
- Involved in cervical softening
What is a Low Oestrogen-Progesterone Ratio? What effect does this have on Prostaglandins?
- Progesterone>Oestrogen
- Low Prostaglandins
What is a High Oestrogen-Progesterone Ratio? What effect does this have on Prostaglandins?
- Oestrogen>Progesterone
- Increased Prostaglandins
What is Oxytocin?
Oxytocin is a peptide hormone, as an important role in many human behaviours including sexual arousal, recognition, trust, romantic attachment and mother–infant bonding
Where is Oxytocin secreted from?
- Secreted by posterior pituitary
- Controlled by hypothalamus
What is the Ferguson Reflex?
A neuroendocrine reflex in which the foetal distension of the cervix stimulates a series of neuroendocrine responses, leading to oxytocin production