Lecture 8 - Mitosis Flashcards
1
Q
what is mitosis?
A
- cell division where 2 identical daughter cells are produced form a parent cell, both with identical copies of DNA as the parent cell
- important for asexual reproduction
- occurs in somatic cells
2
Q
what can happen if there is disruption of cell cycle?
A
Cancer can occur. Cancer can also be genetic
3
Q
karyokinesis
A
when genetic material is separated into daughter cells during nuclear division (P,M,A and T)
4
Q
what is after karyokinese
A
cytokinesis, which is when the cytoplasmic division occurs
5
Q
What happens in prophase?
A
- chromosomes condense; they become visible
- nucleoli dissolves
- centrosomes move apart towards opposite poles and microtubules are generated
6
Q
What happens in prometaphase?
A
- nuclear envelope disintegrates
- allows the microtubules to enter the nucleus
- sister chromatids attach from opposite centromeres
7
Q
What happens during metaphase?
A
- chromosomes align on the metaphase plate/equator
- sister chromatids directed towards opposite poles
8
Q
What happens during anaphase?
A
- chromosomes break at centromeres
- sister chromatids move to opposite ends of cell
9
Q
What happens during telophase?
A
- nucleoli & nuclear membrane reform
- spindle fibers disintegrate
- chromosomes uncoil into diffuse chromatin
10
Q
What is the significance or importance of mitosis?
A
- keep chromosome # consistent
- maintains genetic stability in daughter cells
- helps in growth and development of zygote
- helps in repair and regenertaion
- restores “nucleo-plasmic ratio”
- checks cell size & maintains favourable surface area/volume ratio
