Lecture 11 - Pedigree Analysis II

Question 1

What are the assumptions made while analyzing pedigrees?

Answer 1

1. complete penetrance
2. rare-in-population
3. not-y-linked

Question 2

complete penetrance

Answer 2

individual is affected when they have at least one dominant allele of a dominant trait or two recessive alleles of a recessive trait

Question 3

rare-in-population

Answer 3

generally the trait in question is rare in the general population

Question 4

hemizygous

Answer 4

individual having only one copy of a particular gene or chromosome region