Lecture 8 Endocrine Flashcards
what hormones come from the posterior pituitary?
ADH
oxytocin
what hormones come from the anterior pituitary?
GH
ACTH
TSH
FSH and LH
prolactin
what controls the pituitary gland?
hypothalamus
what hormones are insufficient in hypopituitarism
TSH
GH
ADH
what causes diabetes insipidus?
hypopituitarism of the posterior pituitary because ADH is low
what are the clinical manifestations of DI
weight loss
polyuria w/ low spec gravity and low osmolarity
extreme thirst
hypovolemia
hypernatremia
low BP
what are the diagnostic tests for DI?
urine osmolarity - normal is 200-800
specific gravity - normal is 1.005-1.025
how is DI treated?
desmopressin
fluid replacement
identify and correct underlying cause
what condition comes from hyperpituitarism?
SIADH
increased ADH
what can cause SIADH
pituitary tumor is most common
lung cancer, pneumonia, pneumothorax, tumors, head injury, medications
clinical manifestations of SIADH
weight gain
oliguria
increased spec gravity and osmolarity
hypervolemia
hyponatreamia
diagnosing SIADH
urine specific gravity and urine osmolarity
how is SIADH treated?
reverse the cause
restrict fluid
diuretics
hypertonic fluids for severe hyponatremia
what to monitor for SIADH
s/s of fluid overload
daily weights, I/Os
s/s of hyponatremia and neuro status
how is pituitary tumor diagnosed?
MRI
CT
pituitary hormone labs