Exam 1 Flashcards
what is the most common chronic disease in adults?
hypertension
normal BP
120/80
elevated BP
120s/ less than 80
HTN stage 1
130s/ 80s
HTN stage 2
140/90
hypertensive crisis
180/120
normal cardiac output
4-6 L
peripheral vascular resistance
resistance of arteries to blood flow
- elasticity of arterial wall
- diameter of arteries
- blood viscosity
equation for BP
CO x PVR
what do signs and symptoms of hypertension indicate?
target organ damage has already occured
signs and symptoms of hypertension
headaches
fatigue
epistaxis
vision loss
chest pain
palpitations
SOB
renal failure
TIA, stroke = hemiplegia, speech difficulties
rate to deflate BP cuff
2-3 mm Hg per second
measuring BP considerations
- avoid smoking, caffeine, activity 30 mins prior
- empty bladder
- both feet on ground
- sit quietly for 5 mins
BP goal for hypertension
130/80
first line HTN medications
- thiazides
- ACE inhibitors
- ARBs
- Calcium channel blockers
second line HTN medications
other diuretics
beta blockers
alpha blockers
direct renin inhibitors
vasodilators
evidence of target organ damage in hypertensive emergency
MI
dissecting aortic aneurysm
intracranial hemorrhage
coronary arteries
Left main artery
Left anterior descending artery
Left circumflex artery
Right coronary artery
what kind of plaque is more dangerous?
a plaque with a thin cap because it is prone to rupture and cause embolic event
clinical manifestations of CAD
epigastric distress
SOB
radiating pain
angina
women’s manifestations of CAD
indigestion
N/V
palpitations
numbness
back pain
metabolic syndrome
Enlarged waist circumference
Elevated triglycerides
Low HDL
HTN
Elevated FBG
Normal lipid profile
cholesterol <200
triglycerides <150
LDL <100
HDL >40-50
medications for hyperlipidemia/ cholesterol
Statins
Fibrates
Bile acid sequestrants
cholesterol absorption inhibitor
PCSK9 agents
when to check blood sugar
wake up, before bed
before food
2 hrs after food
blood sugar targets
80-130 before meals
<180 after meals
why is tobacco bad for HTN
- causes coronary artery vasoconstriction
- increases oxidation of LDLs
- increases clotting
angina precipitating factors: 4 Es
exertion
eating
emotional distress
extreme temps
angina symptoms
anxiety, doom
sweating
lightheadedness
also symptoms listed for CAD
normal troponin levels
< 0.034
ADRs to nitroglycerin
- headache (think vasodilation in migraines)
- tachycardia (compensating for hypotension)
- flushing
- hypotension
unstable angina vs MI
unstable angina = partial occlusion will progress to MI
MI = complete occlusion or vasospasm
EKG for NSTEMI
T wave inversion
ST depression
normal EKG
EKG for STEMI
ST elevation
EKG for unstable angina
normal EKG
Which conditions cause elevated troponin?
NSTEMI and STEMI
respiratory findings of acute coronary syndrome (Unstable angina and MI)
SOB
dyspnea
tachypnea
crackles
when should EKG be obtained
within 10 minutes of arrival to ED
how long does troponin stay elevated after MI?
two weeks
besides MI, what can cause elevated troponin
congestive heart failure
sepsis
what does elevated creatinine kinase indicate?
MI
when does elevated creatinine kinase peak?
within 24 hours of MI
myoglobin
- heme protein that transports O2
- increases for 1-3 hours of MI, peaks within 12 hours
how soon should artery be stented?
within 60 minutes of arrival for STEMI