Kidney Disorders Flashcards
anuria
less than 50 ml UOP in 24 hours
oliguria
less than 400 ml UOP in 24 hours
what is normal GFR
> 60 mL per minute
what is normal BUN
6-24 mg/dL
what is normal creatinine
0.7-1.3 mg/dL
azotemia
abnormally concentrated nitrogen waste in the blood
urinary casts
proteins secreted from damaged kidney tubules
what substances are normally filtered by the kidneys?
electrolytes - sodium, chloride, potassium, calcium, bicarbonate, magnesium, phosphorous
waste products - urea, creatinine, uric acid
glucose
manifestations of fluid deficit
weight loss
decreased skin turgor
dry membranes
oliguria
increased hematocrit and BUN
manifestations of potassium deficit
anorexia
paralytic ileus
EKG changes
dysrhythmias
manifestations of potassium excess
diarrhea
nausea
irritability
EKG changes
weakness
manifestations of hyponatremia
nausea
malaise
lethargy
headache
seizures
manifestations of hypernatremia
dry mucous membranes
thirst
dry tongue
fever
disorientation
what is glomerulonephritis?
inflammation from antibody complexes being deposited in glomeruli
what can cause glomerulonephritis?
GAS
viral infections
autoimmunity
what is the other name for glomerulonephritis?
acute nephritic syndrome
manifestations of glomerulonephritis
azotemia - high nitrogen waste in blood
hematuria, proteinuria, cola colored urine
oliguria
edema, HTN, flank pain, headache, malaise
lab findings for glomerulonephritis
elevated BUN and creatinine
hypoalbuminemia
hyperlipidemia
complications of glomerulonephritis (think fluid excess)
hypertensive encephalopathy
heart failure
pulmonary edema
management of glomerulonephritis
corticosteroids
hypertension management
antibiotics if caused by infection
protein restriction
sodium restriction
strict I/O, daily weight
what is chronic glomerulonephritis?
repeated episodes of acute nephritic syndrome causes kidneys to shrink and develop scar tissue
can progress to stage 5 CKD
symptoms of chronic glomerulonephritis
weight loss
fatigue
irritability
headache, dizziness
GI disturbances
treatment of chronic glomerulonephritis
dialysis
treat fluid and electrolyte imbalances
what is nephrotic syndrome?
glomeruli become more permeable
massive proteinuria
manifestations of nephrotic syndrome
hypoalbuminemia -> generalized edema
hyperlipidemia
complications of nephrotic syndrome
infection
thromboembolism
AKI
atherosclerosis
what is the cause of polycystic kidney disease?
90% of cases are caused by autosomal dominant genetic trait
what is PKD?
fluid filled cysts on the kidneys that cause them to enlarge
this is the most common cause of kidney failure