lecture 7/8 - oxidants and antioxidants, oxidative stress Flashcards
1
Q
How is oxidative stress implicated in diabetes?
A
Hyperglycaemia drives oxidative stress, which disrupts metabolic signalling and causes AGE and RAGE processes
2
Q
What is a free radical?
A
A molecular species with one or more unpaired electrons that can initiate chain reactions by moving electrons from other molecules
3
Q
What is a reactive oxygen species?
A
A chemical species that is able to react with targets to oxidise them
4
Q
What are some exogenous sources of antioxidants?
A
Vitamin E, Vitamin C, carotenoids
