LECTURE 6 LTM Flashcards

1
Q

What is organic amnesia?

A

Memory impairments caused by physical damage to the brain, such as head injuries or neurological diseases.

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2
Q

What was unique about the case of HM?

A

HM’s bilateral medial temporal lobe surgery stopped his seizures but caused severe memory problems.

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3
Q

What type of memory was severely impaired in HM?

A

Retaining new information (anterograde amnesia).

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4
Q

What remained intact in HM?

A

Short-term memory, past memories (up to 3 years before surgery), and some procedural learning.

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5
Q

What is the medial temporal lobe (MTL) responsible for?

A

Formation of new declarative (explicit) memories.

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6
Q

What are two types of amnesia?

A

Anterograde amnesia (difficulty forming new memories) and retrograde amnesia (loss of past memories).

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7
Q

What is Ribot’s Law?

A

Older memories are less likely to be affected by brain damage than newer memories.

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8
Q

What areas of the brain are involved in amnesia?

A

Hippocampus, thalamus, mammillary bodies, and adjacent cortical areas like the entorhinal cortex.

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9
Q

What types of memory are impaired in amnesia?

A

Declarative memories (episodic and semantic).

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10
Q

What types of memory are preserved in amnesia?

A

Procedural memory, classical conditioning, and short-term memory.

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11
Q

What are declarative memories?

A

Conscious memories, including episodic (events) and semantic (facts) memory.

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12
Q

What are non-declarative memories?

A

Implicit memories, such as skills, priming, and conditioning, which don’t require conscious retrieval.

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13
Q

What is episodic memory?

A

Memory for specific events tied to a time and place.

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14
Q

What is semantic memory?

A

General knowledge and facts not linked to a specific time or place.

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15
Q

How do episodic and semantic memories differ in consciousness?

A

Episodic involves autonoetic (self-aware) consciousness, while semantic involves noetic (knowledge-based) consciousness.

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16
Q

What did Vargha-Khadem et al. (2007) find about developmental amnesia?

A

Patients had impaired episodic memory but relatively intact semantic knowledge.

17
Q

What is the relationship between episodic and semantic memory?

A

Episodic memory can support semantic learning, and episodic memories often become semantic over time.

18
Q

What is the dual-process model of episodic memory retrieval?

A

Recollection (detailed, effortful retrieval) and familiarity (automatic sense of knowing).

19
Q

What brain areas support recollection and familiarity?

A

Recollection: hippocampus and related structures. Familiarity: perirhinal cortex and dorsomedial thalamus.

20
Q

What is the binding-of-item-and-context model?

A

The hippocampus binds “what” (perirhinal cortex) and “where” (parahippocampal cortex) information for episodic retrieval.

21
Q

What is the consolidation theory?

A

Memories initially depend on the hippocampus but gradually transfer to cortical networks for long-term storage.

22
Q

What is the multiple trace theory (MTT)?

A

The hippocampus is always involved in episodic memory, with multiple traces forming for older memories.

23
Q

How does damage to the hippocampus affect memory?

A

Severe hippocampal damage can impair recent and remote episodic memories.

24
Q

What is priming?

A

Faster or more accurate processing of repeated stimuli, independent of conscious recollection.

25
Q

What are two types of priming?

A

Perceptual priming (enhanced perceptual processing) and conceptual priming (enhanced processing of meaning).

26
Q

What is repetition suppression?

A

Reduced brain activity for repeated stimuli, reflecting neural efficiency.

27
Q

What did Buckner et al. (1998) find about priming?

A

Priming involves distinct brain areas, such as extrastriate cortex for perceptual priming and frontal cortex for conceptual priming.

28
Q

What is procedural memory?

A

Implicit learning of skills and habits, often independent of declarative memory systems.

29
Q

What brain areas are involved in procedural memory?

A

Cerebellum, basal ganglia, and motor areas.

30
Q

How does classical conditioning relate to non-declarative memory?

A

It involves learning associations between stimuli and responses without conscious awareness.

31
Q

What happens in the absence of a cerebellum during classical conditioning?

A

The conditioned reflex (e.g., eyeblink) cannot be learned, though unconditioned responses remain intact.

32
Q

What is semantic priming?

A

Faster recall of semantically related words, such as responding “apple” after seeing “fruit.”

33
Q

What is the functional role of the mammillary bodies in memory?

A

Supporting recollection, with atrophy leading to deficits in recall tasks.

34
Q

What is the significance of frontal and parietal lobes in memory?

A

They contribute to episodic memory and functional networks supporting long-term retrieval.

35
Q

How do autobiographical and semantic memories differ?

A

Autobiographical memories are personal and episodic, while semantic memories are factual and impersonal.

36
Q

What did neuroimaging studies reveal about memory retrieval?

A

Both recent and remote memories activate the hippocampus, with vividness influencing hippocampal activity.

37
Q

What is repetition priming?

A

Improved speed or accuracy when processing repeated stimuli, often accompanied by reduced brain activation.