Lecture 6 - IV/Inhalational Anesthesia Physio

Question 1

triad of anesthesia =

Answer 1

analgesia, amnesia, skeletal muscle relaxation

Question 2

inhlational anesthesia:

allows rapid access to the ____ and direct effects on the _____ system

Answer 2

brain;

pulmonary

Question 3

IV anesthesia:
immediate access to the ____;

anesthetics are ____ soluble to cross the BBB

Answer 3

vascular system;

lipid

Question 4

generally, anesthetics have what mechanism?

Answer 4

reduce excitability of the membrane

Question 5

stages of anesthesia:

1. ____, without amnesia
2. ______
3. surgical _____
4. _____ depression

Answer 5

analgeisa

2. disinhibition
3. anesthesia
4. medullary (bad)

Question 6

MAC: minimal alveolar concentration required to prevent __ of subjects from ____ in response to a painful stimulus

Answer 6

50%; moving

Question 7

the lower the MAC, the ____ the potency

Answer 7

higher

Question 8

N2O has a ____ MAC, ie ____ potency;

Halothane has a ____ MAC ie, ____ potency

Answer 8

high, low;

low, high

Question 9

factors that decrease MAC (ie increase potency):
\_\_\_ age;
\_\_\_thermia;
acute \_\_\_ intoxication;
\_\_\_\_

Answer 9

increasing;
hypo;
ETOH;
pregnancy

Question 10

what is another name for solubility?

Answer 10

blood gas partition coeffecient

Question 11

drugs with low solubility in blood (ie ____) = _____ partition coeffecient, ____ induction/recovery,_____ potency

Answer 11

N2O;

low, fast, lower

Question 12

drugs with high solubility (ie ____):

____ partition coeffecient, ____ induction/recovery, ____ potency

Answer 12

halothane;

high, slow, high

Question 13

things that increase rate of induction:
____ rate/depth of ventilation
____ pulmonary blood flow

Answer 13

increased, increased