Lecture 6 Flashcards

Cell Metabolism II

1
Q

proteins

A

the basis of cellular function

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2
Q

what are proteins made of

A

collagen, elastin, tubulin

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3
Q

functions of proteins

A

cell structure, enzymes, antibodies, hormone receptors, transports proteins, ion channels

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4
Q

nucleotides

A

the gene sequence blocks for each protein

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5
Q

coding region

A

DNA nucleotide sequence doing for the amino acid sequence of the protein

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6
Q

regulatory regions

A

DNA nucleotide sequences that regulate the expression of the gene (turned on or off)

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7
Q

regulatory regions

A

DNA nucleotide sequences that regulate the expression of the gene (turned on or off)

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8
Q

what makes up nucleotides

A

one nitrogenous base, pentose, and a phosphate group

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9
Q

DNA

A

two strands, double helix, deoxyribose

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10
Q

RNA

A

single strand, pentose is ribose

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11
Q

mRNA

A

messenger RNA

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12
Q

mRNA

A

messenger RNA; copies the anti-sense strand and takes it from the nucleus to the cytoplasm

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13
Q

rRNA

A

ribosomal RNA; from ribosomes attaching to mRNA, completes protein synthesis

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14
Q

tRNA

A

transfer RNA; transports mRNA from nucleus to cytoplasm

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15
Q

example of a gene sequence

A

TAC CCG AGG CGT CCG AAA

made of nucleotides

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16
Q

codon

A

three nucleotides to code for an amino acid

17
Q

sense strand

A

coding strand, the complement to the anti-sense strand (what you start with)

18
Q

anti-sense strand

A

DNA strand used for protein synthesis

19
Q

codon

A

three nucleotides to code for an amino acid

20
Q

transcription

A

in a nucleus; DNA double helix unwound, RNA polymerase binds to the anti-sense strand, RNA polymerase tracks along the DNA strand, runs of the complementary strand of mRNA

21
Q

translation

A

in the cytoplasm; requires messenger RNA, ribosomes, transfer RNAs, amino acids, ATP

22
Q

start codon

A

AUG/methionine

23
Q

anticodon

A

binds to the mRNA codon for the amino acid

24
Q

stop codon

A

UGA

25
Q

chaperones

A

ensures proteins are folded correctly

26
Q

ubiquitin

A

labels incorrectly folded protein for destruction

27
Q

proteasome

A

transforms incorrectly folded proteins into individual amino acids

28
Q

autophagy

A

the process of destroying damaged proteins and other organelles; involves cell’s lysosomes

29
Q

gene therapy

A

DNA carrying a normal gene incorporated into the patient’s cell

30
Q

diploid

A

somatic cells, cells that have two sets of chromosomes

31
Q

somatic

A

cells two sets of chromosomes (body cells)

32
Q

mutation

A

a defective protein that often results in the genetic disease

33
Q

types of mutations

A
  1. the incorrect pairing of bases in DNA replication
  2. insertions of extra bases or deletion of a base during replication
  3. expansion in the numbers of trinucleotide repeats, Huntington’s disease
  4. whole sections of deleted, reverse, or transposed DNA
34
Q

engineered viruses

A

vectors transfer copies of the normal gene into a patient’s cells

35
Q

liposomes

A

lipid bilayer sphere incorporate the DNA into liposomes

36
Q

DNA profiling

A

forensic application, the study of human evolution

37
Q

polymerase chain reaction

A

makes million sof copies of short tandem repeat sections