lecture 6 Flashcards
Passive diffusion of particles
Molecules are in continuous random
motion
• Tend to become evenly distributed over
time (i.e. steady state or equilibrium)
• Known as diffusion
• Concentration gradient (chemical)
• Net diffusion
Net diffusion….
Net diffusion and movement of molecules
down the concentration gradient (from
high to low concentrations)
Fick’s law of diffusion:
• The collective influence of factors on the
rate of net diffusion of a substance across
a membrane
• The magnitude (or steepness) of the
concentration gradient
• The surface area of the membrane
across which diffusion is taking place
• The lipid solubility of the substance
• The molecular weight of the
substance
• The distance through which diffusion
must take place
Passive diffusion of ions
Are electrically charged and other than concentration gradient, there movement Is affected by there electrical charge A difference in charge between two adjacent areas thus produces an
electrical gradient
• The combinatorial effect of the concentration and electrical gradients on
the ion forms the electrochemical gradient
Osmosis
Can readily go through the plasma membrane and slip between the PL molecules.
Movement of water when
a selectively permeable membrane
separates two unequal solute
concentrations (and unequal water
concentration
Or through aquaporins
Driving force is the concentration gradient
Net diffusion for water is known as osmosis
Osmatic pressure
The osmotic pressure of a solution (a “pulling” pressure) is a
measure of the tendency for water to move into that solution
because of the concentration of non-penetrating solutes and water
Hydrostatic pressure
Hydrostatic (fluid) pressure is the pressure exerted by a standing,
or stationary, fluid on an object—in this case, the membrane