9 Flashcards
vesicular transport
For large polar molecules (e.g. protein hormones secreted by endocrine
cells) and multi-molecular materials (e.g. bacteria ingested by white
blood cells) to enter and leave the cell
* Requires energy expenditure by the cell Active mechanism of
transport
* This energy is needed to accomplish vesicle formation and
movement within the cell
Two forms of active transport:
- Endocytosis: three forms depending on the material internalized.
- Pinocytosis
- receptor-mediated endocytosis
- phagocytosis
- Exocytosis
these fuse with lysosome except exocytosis
pinocytosis
nonselective uptake of a sample of ECF) = “cell drinking
Macropinocytosis = large gulps of fluid
receptor-mediated endocytosis
receptor-mediated endocytosis (selective uptake of a large molecule)
phagocytosis
phagocytosis (selective uptake of a multimolecular particle) = “cell eating”
Unlike pinocytosis and receptor
mediated endocytosis, only certain
specialized cells can perform
phagocytosis
Exocytosis
Almost the reverse of endocytosis (NO fusion with lysosomes)
* Two purposes:
* Secretion of large polar molecules (i.e., hormones or enzymes)
* Addition of components to membrane (i.e., channels or receptors)
exocytosis docking..
Docking Marker on vesicle
docking-marker acceptor on
plasma membrane
(v-SNARE t-SNARE)
“Lock-and-key