Lecture 52- Urinary System Part 3 Flashcards
What does RAAS stand for?
Renin
Angiotensin
Aldosterone
System
What do juxtaglomerular cells line?
Afferent arteriole which brings blood to the glomerulus
What cells secrete renin?
Juxtaglomerular cells
What two detections stimulate renin production?
- Drop in blood pressure
- Change in concentration of filtrate
What does renin convert angiotensinogen from the liver into?
Angiotensin I
What enzyme converts Angiotensin I into Angiotensin II in the lungs?
ACE (Angiotensin-converting enzyme)
What is the primary function of Angiotensin II?
Widespread vasoconstriction
Angiotensin II stimulates the adrenal cortex to secrete what?
Aldosterone
What is the function of Aldosterone?
Stimulates sodium uptake in the DCT and collecting duct
What is the effect on water transport when high concentrations of sodium are taken up by the nephron?
How is blood pressure affected?
Water follows salt, so there would be higher amounts of water retention
Increases blood pressure
How does ADH decrease urine volume?
Antidiuretic hormone (ADH) decreases urine volume by increasing the permeability of the collecting ducts to water.
This allows more water to be reabsorbed back into the bloodstream, leading to a decrease in urine volume/highly concentrated
How would urine volume change without ADH?
Increase in volume/more diluted
Why would renin be triggered?
Drop in blood pressure
How would ADH restore a drop in blood pressure?
Increase water reabsorption to the blood which increases blood pressure
True or false:
Alcohol inhibits the release of ADH
True
Leads to increase urine production
