Lecture 5 Flashcards
true or false the bigger the group is the more there are individual differences in pain
true
true or false: when you get a disease or like a surgery do you have high chances of have chronic pain susceptibility
true
what is the % of chronic post surgical pain
7%
what are the two main reasons for interindividual variability
-organismic
-environmental
what are organismic differences?
–genetic backround
-sex
-psychological traits: stable
-age
-circadian rythyms
what are enviromental differences
-past experiences
-gender
-psychological states: unstable
-diet
-legal factors
-social factors
true or false the biological model of pain is true
nah it is false
what is the biological model
it is the model that says oh if your bladder hurts, then your problem is the bladder
what is a study that you can do to see if pain genes are important heritable
-if identical twins not =fraternal twins then the genes are not important
-if identical twins==fraternal genes for pain means environment factors for pain
what is the % of pain genes that are heritable
40%
true or false: mices have the same % of pain genes that are heritable
true
what is an example of a monogenic pain disorder
HSAN aka pain insensitivity
true or false: most pain diseases are omnigenic
true
what is the gene that get the most attention for pain genetics
COMT
what is the study to study temporomandibular disorder aka TMD
the study they took a bunch of people and they knew which % will have TMD and they did a bunch of tests
-PILL and scl 90r somatization were the best tests to know
-both measure somatization which is the perseverating about bodily sensations =2X chances
true or false: osteoarthritis in woman is more before 45
false it is in means, woman is after
why do woman have more chronic pain
-more susceptible to some disease
-doctors treat them differently
-men go to the doctors less
are there sex differences
true
true or false woman said they had more pain when they were tested with men
true and men they say they have less pain with women
monocycline blocks what?
microglia