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Histology > LECTURE 3 | Hematopoietic Tissue > Flashcards

LECTURE 3 | Hematopoietic Tissue Flashcards

1
Q

Unique form of Connective tissue

A

Blood

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2
Q

3 Major Cell types

A
  1. Erythrocytes (RBC’s)
  2. Leukocytes (WBC’S)
  3. Thrombocytes (Platelets)
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3
Q

Determine the percentage of each in blood:

• Plasma
• Buffy Coat
• RBC

A

• Plasma = 55%
• Buffy Coat = 1%
• RBC’S = 45%

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4
Q

Blood cell production

A

Hemopoiesis

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5
Q

The site of hemopoiesis occurs in the different sites of the body, depending on the ____________.

A

Stage of development

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6
Q

The sites of hemopoiesis when it is still an embryo is in the ___________ and later in the development of liver, spleen, lymph nodes, and bone marrow.

A

Yolk sac

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7
Q

In the newborn, all bone marrow is _______ and functions in hemopoiesis.

A

Red marrow

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8
Q

All blood cells originate from a common _________ in the red bone marrow that is self-renewing.

A

Stem cell

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9
Q

During hemopoiesis, some lymphoid cells remain in the bone marrow and migrate via bloodstream to lymph nodes and the spleen, where they proliferate and differentiate into _______________, after which they colonize peripheral lymphoid tissues.

A

B-lymphocytes

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10
Q

Other undifferentiated lymphoid cells migrate to Thymus gland, where they proliferate and differentiate into immunocompetent ___________.

A

T-lymphocytes

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11
Q

These 2 lymphocytes both resides in numerous peripheral lymphoid tissues, lymph nodes, and spleen.

A

B and T lymphocytes

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12
Q

Initiate immune response when exposed to antigens

A

B-lymphocytes & T-lymphocytes

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13
Q

B and T lymphocytes has a different protein markers on their cell surfaces, by what means does it allow to be distinguished?

A

By immunohistochemical means

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14
Q

Delivers oxygen from lungs to the tissues

A

Erythrocytes

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15
Q

Facilitates carbon dioxide transport

A

Erythrocytes

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16
Q

• Acts as buffer and regulates hydrogen ion concentration
• Contributes to blood viscosity
• Carries blood group antigens and Rh factor

A

Erythrocytes

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17
Q

A major blood cell type that is subdivided in Granulocytes and Agranulocytes depending on the absence/presence of granules in their cytoplasm.

A

Leukocytes

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18
Q

What are the 3 leukocytes that belong to the Granulocytes group?

A

✓ Neutrophils
✓ Eosinophils
✓ Basophils

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19
Q

Capture and destroy invading microorganisms

A

Neutrophils

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20
Q

Mediators of inflammation

A

Neutrophils

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21
Q

A leukocytes that move to inflamed areas

A

Eosinophils

22
Q

Leukocytes that traps substances

A

Eosinophils

23
Q

Leukocytes that:

• Killing cells, anti parasitic and bactericidal activity
• participating in immediate allergic reactions
• Modulating inflammatory response

A

Eosinophils

24
Q

The Innate Immune System

A

Eosinophils

25
Q

It combat parasites by release of cytotoxic chemicals, which attack the parasite.

A

Eosinophils

26
Q

What does the eosinophils release to combat a parasite?

A

Cytotoxic chemicals

27
Q

Serve as the immune surveillance

A

Basophils

28
Q

Help detect and destroy some early cancer cells

A

Basophils

29
Q

A leukocytes that release histamine in their granules during an allergic reaction.

A

Basophils

30
Q

Defends against bacterial or fungal infection

A

Neutrophils

31
Q

Most commonly released with early acute inflammation

A

Neutrophils

32
Q

Makes up 60% of total leukocyte count

A

Neutrophils

33
Q

The life span is about 5 days

A

Neutrophil

34
Q

These are inflammatory cells

A

Eosinophils

35
Q

These respond in allergic reactions and parasitic invasions

A

Eosinophils

36
Q

• These are responsible for allergic reactions
• They release histamine which causes vasodilation

A

Basophil

37
Q

These are known as macrophages which are responsible for phagocytosis of pathogenic cells

A

Monocytes

38
Q

They present pathogens to T cells which kill them.

A

Monocytes

39
Q

What are the 2 Leukocytes that falls under the group Agranulocytes?

A

✓ Lymphocytes
✓ Monocytes

40
Q

Helps the body fight cancer and foreign viruses and bacteria (antigen)

A

Lymphocytes

41
Q

Helps our immune system remember every antigen it comes in contact with.

A

Lymphocytes

42
Q

Resides in the blood and tissue to find and destroy germs (virus, bacteria, fungi, protozoa) and eliminate infected cells.

A

Monocytes

43
Q

A leukocytes that call other WBC’s to help treat injury and prevent infection

A

Monocytes

44
Q

Can be found in blood but not a blood cells

A

Thrombocytes (Platelets)

45
Q

Smallest, nonnucleated formed elements appear in the blood of all mammals

A

Thrombocytes

46
Q

Largest cells in the bone marrow

A

Megakaryocytes

47
Q

Membrane bound cytoplasmic fragments or remnants of megakaryocyte.

A

Platelets

48
Q

It continually monitor the vascular system and detect damage to the endothelial lining of the vessels

A

Thrombocytes

49
Q

If there are damage /breaks in the vascular system or in the endothelial lining of the vessels, the platelets will adhere to the damaged site and initiate a highly complex chemical process that produces _________.

A

Blood clotting

50
Q

• They are enucleated (without nucleus) and stain pink with eosin.
• They are uniform in size and measure approximately 7.5 um in diameter, which is the approximate size of the capillaries.

A

Erythrocytes

Histology (8 decks)

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