LECTURE 3: embryology Flashcards

1
Q

when is the PRE-EMBRYONIC STAGE

A

0-14 days

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2
Q

what are the 2 cell layers within the embryonic disk

A

ectoderm and endoderm

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3
Q

when is the EMBRYONIC STAGE

A

15 days - 8 weeks

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4
Q

where does the nervous system develop?

A

ectoderm

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5
Q

when is the FETAL STAGE

A

end of 8 weeks to birth

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6
Q

when does myelination start

A

after 8 weeks

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7
Q

when does the neural tube develop

A

days 18 to 26

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8
Q

where does the Neural plate forms longitudinally from

A

ectoderm

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9
Q

what makes the neural groove

A

edges of plate folds

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10
Q

when does the neural groove fold together and what does it form

A

day 21 and forms the neural tude

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11
Q

where does the neural tube close first

A

cervical region

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12
Q

the tubes Quickly fuses together rostrally/caudally with
open ends called

A

neuropores

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13
Q

where does the neural crest move

A

inside embryo

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14
Q

what cover the tube/crest

A

ectoderm

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15
Q

the superior neurpore closes when

A

day 27

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16
Q

the inferior neuropore closes when

A

day 30

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17
Q

Inner and outer cell layers are formed by the neural tube by day

A

26

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18
Q

where do the cell bodies become gray matter

A

inner layer

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19
Q

how does the tubes separate in the inner layer

A

dorsal/ventral sections

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20
Q

what is the ventral horn responsible for

A

motor

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21
Q

what is the dorsal horn responsible for

A

sensory

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22
Q

what does the outer layer of the neural tube do

A

processes cell bodies

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23
Q

what becomes white matter with axons and glial cells

A

the outer layer

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24
Q

what does the neural crest cells form

A

Peripheral sensory neurons
automatic neutrons
endocrine organs

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25
Q

Cells extend 2 processes, 1 to SC and 1 to dermal part of somite forming

A

dermatomes

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26
Q

Cell bodies of peripheral sensory neurons are ______ SC and in the _______

A

outside
dorsal root ganglion

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27
Q

the anteromedial part of the somite goes wheree

A

vertebrae and skull

28
Q

the posteromediaial somite goes where

A

muscles of myotome

29
Q

the lateral somite goes where

A

dermatome becomes dermis

30
Q

what is the end of the SC

A

conus medullaris

31
Q

what is the nerve roots coming off the end of the SC

A

cauda equine

32
Q

Connection of pia, arachnoid, dura mater from end of SC to coccyx is

A

filum terminale

33
Q

when does the SC stop growing

A

4-5 years old

34
Q

when does the Vertebral column stops growing

A

16-18 yrs

35
Q

when does the brain region start to develop

A

after the closure of superior neurpore

36
Q

what is in the hindbrain

A

medulla , pons , cerebellum , with central canal
forming 4th ventricle

37
Q

in the hindbrain the inner layer cell bodies migrate through what

A

white matter to go to gray matter

38
Q

where does Central canal form the cerebral aqueduct connecting 3rd
and 4th ventricles

A

midbrain

39
Q

where does the Posterior region remains near midline forming diencephalon to include thalamus, hypothalamus

A

forebrain

40
Q

where does the Anterior form telencephalon to become cerebral hemispheres

A

forebrain

41
Q

what does the cerebral hemispheres include

A

basal ganglia , white matter and cortex

42
Q

what forms B LATERAL VENTRICLES

A

central canal of the neural tube

43
Q

T/F : Lateral hemispheric areas do not grow as much as others

A

T

44
Q

what does the edges of the lateral sulcus cover

A

insula

45
Q

what is considered the 5th lobe

A

insular

46
Q

how do neurons travel to final destinations

A

sending an extension to brain surface and then pulling self along the extensions or by climbing along glial cells

47
Q

when do neurons differentiate into special functions

A

after reaching destination

48
Q

the function of the neurons depends on what

A

where it lands

49
Q

when do synaptic vesicles form, microtubules extend beyond growth cone to presynaptic membrane.

A

when growth cones contact their target cells

50
Q

when do the neighboring post-synaptic membrane creates receptor sites

A

as neurotransmitters are released

51
Q

what is likely to happen due to failed connections or too inactive

A

neuronal death

52
Q

how many neurons may go to a single muscle cell during development?
how many neurons may go to a single adult muscle cell?

A

serveral
only one

53
Q

what do neuron connections also do

A

shape development of muscles

54
Q

muscle fiber type is dependent on the type of

A

innervation

55
Q

Myelination of long axons begins in______ with most finished at ____, depending on system

A

4th fetal month

3 yrs

56
Q

when are motor roots of the SC myelinated a

A

1 month

57
Q

when are nerves from the cortex to motor neurons myelinated

A

2 years

58
Q

can a child grow into defects

A

yes

59
Q

• Asymmetric tonic neck reflex
• Symmetric tonic neck reflex
• Tonic labyrinthine reflex

are examples of what

A

Abnormal neck and vestibular reflexes

60
Q

• Anencephaly
• Arnold Chiari malformation
• Spina bifida

what examples of what

A

neural tube defects

61
Q

what happens when abnormal events occur prior to 20 weeks of gestation

A

major deformities of nervous stem will be present

62
Q

what is a big risk factor for lots of neurodegenerative conditions

A

age

63
Q

what cognitive abilities seem to be preserved with an aging brain

A

vocab and comprehension

64
Q

T/F : Normal age-related cognitive changes don’t markedly hinder quality of life

A

true

65
Q

what includes memory loss with/without other cognitive involvement

A

mild cognitive involvement

66
Q

if someone has MCI they are 90% to develope what

A

alzheimer’s disease within 5 year s