extar fro exam 1

Question 1

what are the 2 mechanisms receptors use to transduce signals

Answer 1

ligand gated ion channels (fast response ) ( asak iontroptic receptor)
G protiens which trigger ion channels (slow and aka metabotropic receptor)

Question 2

what is the lock and key analogy

Answer 2

the neruotransmitter (key) must fit into the receptor site (lock)

Question 3

when do ligand gated ion channels open

Answer 3

when neurotransmitters bind to post syanptic receptors

Question 4

when neuromodulators bind at extracellular receptor , it initiates a sequence of intracellular events with what as the 2nd messenger

Answer 4

G protein

Question 5

what are examples of amino acids

Answer 5

ACH
glutamate
GABE

Question 6

what are examples of amine

Answer 6

dopamine
norepinerphrin
serotonin

Question 7

all neurosn that synapse with skeletal muscles use ____ to electi fast acting effects on muscle membranes

Answer 7

ACH

Question 8

where is ACH found in muclses

Answer 8

at NM junction

Question 9

is ACH excitatory or inhibitory

Answer 9

excitatory

Question 10

what disease destroys recptors for ACH

Answer 10

myasthenia gravies

Question 11

what NT is implicated in nicotine addiction and alzheimers disease

Answer 11

ACH

Question 12

what inhibits postsynaptic membranes mostly in the BS and SC

Answer 12

glycine

Question 13

where does substance P act as a neurotransmitter and neuromodulator

Answer 13

CNS and in pain syndrome