Lecture 3

Question 1

What are the 5 classic signs of inflammation ?

Answer 1

1. Pain
2. Swelling
3. Redness
4. Heat
5. Loss of function (optional)

Question 2

What is the difference between transudate and exudate ?

Answer 2

Transudate is the typical mix of fluid and electrolytes that comes out of the microcirculation.
Exudate is plasma protein rich fluid that comes out of the microcirculation due to increased permeability + higher blood flow (as a result vasoactive mediators released during inflammation.)

Question 3

What is Hyperemia ?

Answer 3

Increased blood flow due to dilation of vessels (as a result of the release of vasoactive mediators during inflammation.)

Question 4

What are the main vascular changes occurring during inflammation ?

Answer 4

1. Increased Permeability.

2. Hemodynamic changes.

Question 5

What is Margination ?

Answer 5

The adhesion of leukocytes on the endothelial cell walls as a result of the dilation of capillaries.