Lecture 22 Flashcards
1
Q
What are the type of cells that you find in the epidermis ?
A
Melanocytes.
Nerve endings
Langheran cells.
2
Q
What are the type of cells that you find in the dermis ?
A
Nerve cells
Hair follicles
Mast cells
Langheran cells.
3
Q
What is hypersensitivity type 1?
A
A reaction to an allergen that triggers IgE to degranulate mast cells, and provokes an inflammatory + immune reaction.
There is a genetic predisposition to this, where the barriers of the epidermis is compromised due to abnormal junctions, secretions and filaments.
4
Q
What is immune complex deposition ?
A
A variant of celiac disease.
Exposure to gluten leads to production of IgA antibodies which accumulate at the epidermal-dermal barrier, form aggregates and trigger an inflammatory reaction.
