Lecture 3 Flashcards

1
Q

propulsive movement

A

push contents forward through the digestive tract

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2
Q

mixing movement

A

promote breakdown and facilitate absorption across the digestive wall

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3
Q

mechanical digestion

A

physical mixing and churning that breakdown large masses of food into smaller masses of food

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4
Q

chemical digestion

A

using enzymes to break bonds of large molecules into small molecules

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5
Q

why is it important to break down food physically

A

to increase surface area for enzyme action

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6
Q

main enzyme in saliva

A

amylase (alpha 1-4 bonds in starch)

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7
Q

other components of saliva

A

electrolytes, lingual lipase

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8
Q

purpose of mucus

A

lubrication
protect gut wall from digestive enzymes

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9
Q

order of layers

A
  1. lumen
  2. mucosa
  3. muscularis externa
  4. serosa
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10
Q

mucosa

A

innermost mucous membrane layer
produces and releases secretions needed for digestion
lymphoid tissues protect the body

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11
Q

submucosa

A

connective tissue w/blood vessels, lymphatic vessels, nerves, and lymphoid tissue

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12
Q

muscularis externa

A

two layers of smooth muscles
- longitudinal and circular
- responsible for GI motility

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13
Q

serosa

A

connective tissue
outer cover that protects the GI tract

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14
Q

bolus components

A

food and saliva

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15
Q

_____ grinds and mixes food w/gastric juice to form _____

A

antrum, chyme

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16
Q

how does volume affect motility of the stomach

A

when full, motility and emptying is stimulated

17
Q

fluidity affect motility of stomach

A

when more broken down, chyme is easier to move, and emptying will be stimulated

18
Q

how do high levels of fat, acid, distension of small intestine affect motility of the stomach

A

inhibits emptying until the small intestine can process more

19
Q

how does stress impact motility of the stomach

A

inhibits motility and emptying via sympathetic nervous system

20
Q

cardia

A
  • part near esophagus
  • contains cardiac glands
21
Q

pylorus

A
  • part priximal to pyloric sphicter
  • contains pyloric glands
22
Q

fundus/body

A
  • between cardia and pylorus
  • contains fundic/gastric glands
23
Q

cardiac glands

A
  • mainly mucus cells
  • some entereoendocrine cells interspersed
24
Q

pyloric glands

A
  • mucus cells
  • entereoendocrine cells (g and d cells)
25
gastric glands
- parietal cells - chief cells - mucus cells - entereoendocrine cells (g cells)
26
parietal cells
- gastric acid (HCl) - intrinstic factor (Ca+++ absorption)
27
enterochromaffin like cell
- histamine (stimulates acid)
28
chief cells
- pepsin (ogen) - gastric lipase
29
D cells
- somatostatin (inhibits acid)
30
G cells
gastrin ( stimulates acid)
31
gastric juice
- Hcl - pepsinogen (inactive precursor of pepsin) - Intrinsic factor - gastrin - lipase - amylase
32
HCl functions
1. converting pepsinogen to pepsin denaturing proteins killing bacteria ingested with food releasing nutrients from organic complexes
33
main proteolytic enzyme in the stomach
pepsin
34
absorption in the stomach
limited
35
what causes the breakdown of vitamin b12 bound to food
acidic environment of the stomach
36
percentage of oxygen molecules at any iven altitude
21%
37
saliva compoentns
water (99.5%) salivary amylase electrolytes lingual lipase
38
gastro-esophageal sphincter
connects esophagus and stomach
39
pyloric sphincter
connects stomach to duodenum