Lecture 3 Flashcards

1
Q

what is hematopoiesis

A

the production of blood cells AND platelets

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2
Q

what is whole blood composed of

A

fluid and cells

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3
Q

what is the fluid part of whole blood called

A

plasma

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4
Q

what makes up the cell component of whole blood

A

RBCs
WBCs
Platelets

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5
Q

what are erythrocytes

A

red blood cells

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6
Q

what are leukocytes

A

white blood cells

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7
Q

five kinds of WBCs (leukocytes)

A

neutrophils
eosinophils
basophils
monocytes
lymphocytes

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8
Q

what are thrombocytes

A

platelets

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9
Q

two categories of white blood cells

A

agranulocytes
granulocytes

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10
Q

what WBCs make up agranulocytes

A

Lymphocytes
Monocytes

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11
Q

what WBCs make up granulocutes

A

Neutrophils
Eosinophils
Basophils

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12
Q

what does morphology mean

A

cellular appearance (shape)

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13
Q

multipotent primitive cells that can develop into all types of blood cells

A

Hematopoietic Stem Cell (HSC)

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14
Q

two locations where Hematopoietic Stem Cells (HSC) can be found

A

bone marrow of the long bones

some in the spleen

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15
Q

any of a number of substances, such as interferon, interleukin, and growth factors, which are secreted by certain cells of the immune system and have an effect on other cells.

A

cytokine

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16
Q

stem cell that produces one of the three mature blood cells

A

Myeloid

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17
Q

stem cell that produces lymphocytes (plasma cells)

A

lymphoid

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18
Q

Production of erythrocytes

A

Erythropoiesis

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19
Q

Production of leukocytes

A

Leukopoiesis

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20
Q

Production of thrombocytes

A

Thrombopoiesis

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21
Q

the cytokine responsible for production of RBCs, produced by the kidneys

A

Erythropoietin (EPO)

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22
Q

RBCs become ________ as they mature, lose their ______ and gain __________

A

smaller
nucleus
hemoglobin

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23
Q

RBC development slide

24
Q

immature RBCs

A

reticulocytes

25
thrombopoietin is primarily produced where
the liver
26
hematopoietic cells, which are responsible for the production of blood platelets
Megakaryocyte
27
fragments of the cytoplasm of megakaryocytes
platelets
28
stopping the flow of blood
hemostasis
29
stimulates the bone marrow to increase the rate of leukopoiesis
leukopoietin
30
Granulopoiesis: Large with round to oval nucleus, prominent nucleolus, pale gray–blue cytoplasm
Myeloblasts
31
Granulopoiesis: Horseshoe-shaped nucleus with parallel sides
Band cells
32
Granulopoiesis: Nuclei with 2 or more lobes – heads to circulation
Segmented granulocytes
33
Most common WBC Job is to defend the body against bacterial infection
neutrophils
34
neutrophils
35
eosinophils
36
basophils
37
Present in low numbers or not at all in healthy animals Often increases in an animal due to parasitic organisms or allergies
eosinophils
38
Rarely seen in healthy animals Associated with allergic disease and parasitic infections
basophils
39
Present in low numbers in peripheral blood Increase with chronic inflammation Increase with stress in the dog Tissue repair Help regulate immune response Phagocytosis of dead cells and microorganisms
monocytes
40
three kinds of lymphocytes
T lymphocytes B lymphocytes Natural Killer Cells
41
Functions in acquired immunity (memory)
lymphocytes
42
1.
erythrocyte
43
2.
lymphocyte
44
3.
neutrophil
45
4.
eosinophil
46
5.
basophil
47
6.
monocyte
48
7.
platelets
49
1.
Band neutrophil (leukocyte)
50
2.
Eosinophil (leukocyte)
51
3.
segmented neutrophil (leukocyte)
52
4.
basophil (leukocyte)
53
5.
lymphocyte (leukocyte)
54
6.
monocyte (leukocyte)
55
what do cells become after it has been stimulated to develop into an erythrocyte
rubriblasts
56
what rubriblasts become as they continue to divide (three steps)
prorubricytes > rubricytes > metarubricytes
57