lecture 28 - motor systems: spinal cord and brain stem Flashcards
what are the 4 classifications of movement?
reflexive, postural balance, volitional (reaching for a cup), and repetitive (walking)
list reflexive, volitional and postural balance in order from most automatic to least automatic
reflexive, postural balance, volitional
what are two divisions of the motor system
lateral and medial motor systems
describe the descending lateral pathway
cerebral cortex –>
- cerebellum –> red nucleus
- basal ganglia –> red nucleus
- directly to the red nucleus
- -> sc
what is the descending lateral pathway?
rubrospinal
what are the 3 descending medial pathways?
vestibulospinal, reticulospinal, tectospinal
describe the descending medial pathways
cerebral motor cortex –> cerebellum/basal gang/direct –>
vestibulospinal: vestibular nuclei –> sc
reticulospinal: reticular formation –> sc
tectospinal: superior colliculus –> sc
provide a general overview of the ascending pathways of the motor system
cerebellum/basal ganglia –> thalamus –> cerebral cortex
what is a motor unit?
combination of a motor neuron and the muscle fibers it innervates
what are the rules for motor units?
- many motor neurons target each muscle
- each motor neuron targets only one muscle
- each muscle fibre is only innervated by one motor neuron
- when a motor neuron fires, all its fibers contract
what is a motor neuron pool?
collection of motor neurons whose axons all connect to the same muscle, although the neurons may be scattered across different levels of the sc
describe changes between the normal state and neurogenic disorders
loss of motor neurons
describe changes between the normal state and myogenic disorders
muscle fibre degeneration
describe the muscle at rest in its normal state, in neurogenic disorders and in myogenic disorders
normal: at rest
neurogenic: fibrillation
myogenic: fibrillation
describe the muscle during slight contraction in its normal state, in neurogenic disorders and in myogenic disorders
normal: regular, spaced out contractions
neurogenic: one giant contraction, lots of small irrgeular ones
myogenic: fibrillation: small polyphasic units (smaller and more irregular than normal)
describe the muscle during maximal contraction in its normal state, in neurogenic disorders and in myogenic disorders
normal: regular
neurogenic: reduced inference pattern
myogenic: full inference pattern but not as much range
describe histochemical changes from motor neuron loss
- motor neuron dies
- muscle fibres dennervated and die/atrophy
- axons of surviving neurons tend to sprout and innervate dennervated fibres
- muscle fibre types become clustered
is neuronal regeneration in the PNS slow or fast
slow
why can neuronal degernation occur in the motor system of the PNS?
because the targets are promiscuous
motor unit innervates multiple muscles, while sensory fields are less well-defined
explain the process of neuronal regeneration in the PNS
- begins with injury to peripheral nerve
- macrophages arrive and rapidly remove myelin debris
- neuron expresses growth related genes
- proliferating schwann cells promote axon regeneration
what are the two types of muscle spindles
primary and secondary
describe primary muscle spindles
largely respond to velocity of stretch
describe secondary muscle spindles
largely respond to muscle length
gamma motor neurons change what with respect to muscle spindles?
the excitability of spindle responses
describe the deep tendon reflex
monosynaptic excitation of the agonist, disynaptic inhibition of the antagonist
(sensation immediately results in reflex)
what would result in an increased deep tendon refelx?
upper motor neuron lesions
what would result in a decreased deep tendon reflex?
- acute upper motor neuron lesions
- peripheral, sensory, motor neuron and/or muscle abnormalities
what muscles/tendons are involved in the upper extremity deep tendon reflex?
biceps, brachioradialis, triceps, patellar, achilles tendon
what is the corresponding nerve root for the biceps?
C5, C6
what is the corresponding nerve root for the brachioradialis?
C6
what is the corresponding nerve root for the triceps?
C7
what is the corresponding nerve root for the patellar?
L4
what is the corresponding nerve root for the achilles tendon?
S1
what is the function of the flexor reflex?
acts to lift foot away from painful stimuli
what is excited and what is inhibited during the flexor reflex?
flexors = excited extensors = inhibited
what is the function of the crossed extensor reflex?
acts to support the body on the other leg (when lifting one up for flexor reflex)
what is excited and what is inhibited during the crossed extensor reflex?
excited = extensors inhibited = flexors
do the flexor and the crossed extensor reflex go hand in hand
yes
what generates the pattern of muscle leg activity?
central pattern generator in the spinal cord
is the lateral vestibular nucleus ipsilateral or bilateral?
ipsilateral
is the medial vestibular nucleus ipsilateral or bilateral?
bilateral
what is the function of the lateral vestibular nucleus?
maintaining equilibrium, posture and vision w movement
what is the function of the medial vestibular nucleus?
head and neck position
is the pontine reticular formation ipsilateral or bilateral?
ipsilateral
is the medullary reticular formation ipsilateral or bilateral?
ipsilateral
what is the function of the pontine reticular formation?
posture and gait-related movement
what is the function of the medullary reticular formation?
posture and gait-related movement
is there a relationship btwn voluntary motor action and whole-body postural control?
- yes - coordinate
- e.g., leg muscle turns on to stabilize the body before a voluntary arm movement
is the superior colliculus ipsilateral or bilateral?
trick question! its contralateral
what is the function of the superior colliculus?
coordination of the head and neck
is the red nucleus ipsilateral or bilateral?
contralateral
what is the function of the red nucleus?
coordination of sensorimotor info (limb control)
2 posturing reflexes are associated with coma, true or false?
true
describe flexor posturing during coma
patient flexes inwards (arms come into chest)
describe extensor posturing during coma
patient flexes out (arms flex down at sides)
flexor posturing is associated with what?
function above red nucleus (midbrain)
extensor posturing is associated with what?
function below the red nucleus (midbrain)
hint fot posturing during coma?
the higher the arms the higher the function