Lecture 26 + DLA 20 Flashcards
1
Q
What does Hardy- Weinberg assume?
A
- population is large
- random mating
- no new mutations in the population
- no migration of people into the population
2
Q
What are factors that lead to genetic variation
A
- new mutation
- natural selection
- genetic drift
- consanguinity
3
Q
What is an example of heterozygote advantage?
A
sickle cell disease
4
Q
What is the Hardy-Weinberg equation?
A
p2 + 2pq + q2 = 1
5
Q
What does p represent?
A
The functioning allele (homo)
6
Q
What does q mean?
A
The disease causing allele (homo)
7
Q
What group of people make up 2pq?
A
Carriers in the population
8
Q
What is the founder effect?
A
A new mutation is presented into a small population by immigration or just a new mutation
9
Q
What is genetic drift?
A
The allele may be lost or established by isolation of a population
especially if the population is small, the allele frequency may increase
10
Q
What is genetic bottleneck?
A
A reduction in population that leads to a decrease in genetic diversity
