Lecture 25: Renal Injury Flashcards
The urine allows us: (3)
Describe renal histology.
Recall the following renal tissue histology.
Recall the clinical syndromes of renal injury.
Describe haematuria, proteinuria, and acute renal failure.
Recall the important causes of acute and chronic renal injury.
______________________ is the most common cause of Acute Renal Failure
Acute ischaemic tubular necrosis is the most common cause of Acute Renal Failure
Describe acute ischaemic tubular necrosis
- Acute ischaemic tubular necrosis is the most common cause of Acute Renal Failure
- Tubular epithelial cells die
- Tubules dilate
- Sloughed epithelial cells lie in lumen
- Tubular function impaired
- Other components (glomeruli, vessels, interstitium) preserved
- Renal function recovers (if patient survives)
- NB: generally called ‘Acute Kidney Injury / AKI’
____________ are very resistant to iscahemic injury. ____________________ are sensitive to ischaemic injury.
Glomeruli very resistant to ischaemic injury. Tubular epithelial cells sensitive to ischaemic injury
Describe glomerulonephritis
Recall the prognosis of acute glomerulonephritis.
Recall histology showing severe acute glomerulonephritis with the formation of two crescents
Can glomerulonephritis occur without immune response.
Most renal infection are ___________________ coming up from bladder.
ascending gram negative bacterial infections
Describe pyleonephritis
Describe acute pyelonephritis symptoms.
Describe acute interstitial nephritis.
Describe renal deposits.
Recall the following histology of normal glomerulus.
Recall en example of genetic condition of the kidneys.
Describe alport syndrome.
Recall effect of hypertension of kidney.
Describe ‘Benign’ Nephosclerosis
