Lecture 25 - Myocarditis Flashcards
Janeway lesions typically occur on the soles of the feet and palms of the hand, while Osler’s nodes typically occur in the finger tips and toe tips. Which of these associated with Acute endocarditis and which of these is painful?
Janeway is associated with Acute, and Osler’s nodes are painful.
Staph aureus is associated with _____ endocarditis, while Strep viridans is associated with _____ endocarditis.
Acute
Subacute
The number one symptom of Myocarditis is ______ from increased pulmonic pressure.
Dyspnea
What will a coronary angiogram show for a patient presenting with Myocarditis vs a patient presenting with MI?
No coronary blockage!
What is elevated in patients with Myocarditis vs Endocarditis?
Cardiac enzymes (Troponin and DH)
In acute myocarditis, myocytes undergo damage and apop via cell-mediated cytotoxicity. In Chronic myocarditis, myocyte destruction is mediated by their abnormal expression of ______ (autoimmunity).
HLA
______ myocarditis has MUCH higher survival rates than _____ or _____ once patients get beyond the first 2 weeks. Lymphocytic infiltrates persist in the latter two.
Fulminant
Acute
Chronic
____ cell myocarditis is the most severe and is the MAJOR cause of Fulminant myocarditis. This requires Advanced Heart Failure therapies!
Giant cell (Giant cell is a Giant problem)
_______ myocarditis typically occurs in older patients (>58 years old), and is most often medication induced. Look for fever and rash in these patients. What is the treatment?
Eosinophilic myocarditis
Treatment is high dose Steroids and Azathioprine (immunosuppressant)
______ myocarditis is a non-caseating granulomatous myocarditis of unknown etiology. Treatment consists of corticosteroids.
Sarcoid myocarditis
_____ myocarditis is the most common. Treatment involves treatment for heart failure.
Lymphocytic myocarditis
In cases where myocarditis is suspected and the patient is VERY sick, a _____ should be done right away to determine if it is Giant cell myocarditis.
Biopsy