Lecture 25-27: Reproductive System Flashcards
Sex organs in 5-week embryos
Undifferentiated; the genital tubercle, glans, urethral folds, labioscrotal swelling, and perineum start to develop.
Sex organs in 10-week embryos
Starting of differentiation in glans and urethral folds; perineum connected to anus. Not enough to tell the sex yet.
Sex organs right before birth in embryos
Have completely differentiated.
Hypospadias
Urethra not connected to bladder. Surgically fixed at birth.
Sex organs between 10 weeks and birth in males
The testes, epididymis, mesonephric duct (later the spermatocord), and prostate develop. Right before birth the testes descend into scrotum and prostate develops.
Müllerian duct
Degenerates in males after 10 weeks; becomes the fallopian tubes in females.
Sex organs in female right before birth.
Sex organs descend, but stay internal.
Hermaphroditism
Caused by abnormal chromosomes; results in a person having somewhat both sets of sex organs.
Sperm movement
Sperm and fluids go through tubules and ducts to the epididymis. There, the sperm mature and goes through the vas deferens to ejaculatory duct.
Scrotum
Means “bag”. It holds the testes; superficial fascia (dartos) contracts the scrotum to the body for warmth.
Cryptorchidism
Testes/testicles fail to descend. Can lead to sterility and testicular cancer. Can be corrected by surgery or hormone injection.
Spermatogensis
At puberty, spermatozoa begin to be made in the seminiferous tubules.
Cremaster
Involuntary muscle; pulls testes closer to the body for warmth.
Epididymis
Sperm, brought by efferent ducts into the epididymis. It matures for two weeks, increasing motility. The epididymis has smooth muscle to move sperm along.
Function of ejaculatroy duct
During ejaculation, sperm is pushed out into the urethra.
Functions of seminal vesicles
Secrete nutritive and protective fluids for the spermatozoa. The semen protects the sperm and levels the acidity of the vagina.
Cowper’s glands functions
Secrete an acid-neutralizing fluid for the urethra.
Chromosomes
Normally are 23.
Mitosis
When daughter cells divide with full chromosome sets. If they divide completely, the result is identical twins.
Diploid
Cell with two sets of chromosomes. Like somatic cells/normal body tissue.
Haploid
Cell with one set of chromosomes like germ cells.
Parts of the sperm
Sperm head (pierces egg); nucleus (w/ one set chromosomes); tail for propelling
Male-female analogs
Foreskin-prepuce Glans-clitoris Scrotal skin/hair-labia majora Prostate-Skene's glands Cowper's glands-Bartholin's glands
Parts of the vulva, aka pudendum
Prepuce; clitoris; labia majora (external skin folds); labia minora; vestibule
Labia majora and labia minora
Labia majora: “large lips”, are external skin folds
Labia minora: “small lips”, secrete oil
Parts of the vestibule
Hymen, vaginal orifice, external urethral orifice, Skene’s glands, Bartholin’s glands
Parts of internal genitalia (female)
Uterus, vagina, fallopian tubes, ovaries
Functions of the vagina
Receiver of spermatozoa; birth canal
Functions of the uterus
Takes sperm to the ovum; holds developing zygote
Zygote
A fertilized ovum
Parts of the uterus
Fundus (superior); corpus (body/midsection); cervix (neck). Endometrium (covers the muscles of the uterus) and myometrium (muscular lining of uterus).
Cervical os
Cervix’s opening. A mucous plug plugs it except during fertile period.
Uterine cancer
Cander of endometrium
Fibromas (leiomyomas)
Benign tumors in the uterine wall.
Uterine prolapse
When the uterus moves excessively downwards, typically because of age.
Human papilloma virus (cervical cancer)
Sexually transmitted disease
Functions of the fallopian tubes
Carries ovum to the uterus.
Parts of the fallopian tubes
Infundibulum; ampulla (mid-portion/widened part); isthmus (leads to uterus).
Functions of follicles
Primary follicles, after developing from primordial follicles, contain oocytes. The ovum comes from the graafian follicle. When the graafian follicles burst, they release eggs into fallopian tube. All nurture developing oocytes.
Corpus luteum
“Yellow body”. From ovulation and estrogen, progesterone, relaxin, and inhibin come from this.
Corpus albicans
“White body”. The remains of degenerating follicle.
Things that happen during menstruation
Some secondary follicles start to mature in ovaries
Breasts
Aka mammary glands. Are modified sweat glands.
Parts of the breasts
Lobules in lobes; nipple; areola; ducts; ligaments; breast tissue and fat.
Lactation (milk letdown)
Oxytocin controls it; prolactin, estrogen, and progesterone are involved in producing milk.
When does further cell division trigger?
It results in creating a blastocyst that implants in the uterine wall.
Totipotential/pluripotential
Cells that can become any type of cells (like blastocyst cells). The cells will become specific type of cells, specializing during development.
The embryonic neural crest is the start of…
Nervous tissue and vertebra
Amniocentesis
A test that works by draining some amniotic fluid from the amniotic sac that is around the embryo. It can determine abnormalities. 8-10 weeks.
Trisomy 21
Down Syndrome
Meningomyelocele
When the neural crest does not close.
Chorionic villi sampling
Small pieces are taken from the placenta in a 14-16 week range.
DNA
Four components are C, G, A, T. Only about 10% has functional use.
Somatic cells
DNA is Diploid; each cell has whole DNA amount. Mutations in cell are only transmitted along a particular cell line.
Germ cells
DNA is haploid; has only one side of genetic component (male or female). Mutations are in every cell of offspring.
Define genetic
DNA changes in any cell.
Define inherited
DNA changes that is passed through germ line; all cells will show it.
Define congenital
At birth; it can be genetic and/or inherited
Genes
Where in the nuclear DNA that have instructions of body processes; gene proteins carry them out.
Define genotype
The genetic makeup of a cell in regard to its complement of genes.
Define phenotype
How the body expresses its complement.
Pairs of chromosomes
Called homologues.
Alleles
Genes that are on the same location on a chromosome for the same trait.
- Dominant alleles: trait expressive
- Recessive alleles: dominant allele overrides. Most harmful genes.
- Incomplete dominance: cell has both dominant and recessive genes.
Homozygous
When a trait has similar alleles at a specific place.
Heterozygous
When cells at a specific point are different. Heterozygous gene pairs results in incomplete penetrance.
Punnett square
Matrix with all types of allele variations.
Sex chromosomes
C23 is either X or Y. Male: XY; Female: XX. In females, one X chromosome is deactivated; only one active X.
Chromosome Y traits
Y starts male differentiation. Can be used to trace genetics way back.
Turner’s syndrome
No second X chromosome in females; the results are sterility and small size.
Klinefelter’s syndrome
Males get and extra X chromosome. Results in sterility, slight mental retardation, and breast enlargement.
Metafemale
Three X chromosome; results are mental retardation, sterility, underdevelopment.
Non-disjunction
When chromosomes do not separate during meiosis. Results in abnormal numbers of chromosomes in cells
Meiosis
Cell division that results in four daughter cells and 1/2 the number of chromosomes that the parent cell has.