Lecture 24 Flashcards

1
Q

First stage of formation of the heart the formation of the (2) from the…

A

pleuropericardial cavity and cardiogenic plate from the lateral mesoderm

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2
Q

formation of the simple, tubular heart includes _____ which is when ______

A

head folding

tissues in from of neural plate are inverted 180 degrees

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3
Q

What does the 4 chambered heart arise from, what are the first chambers to be created

A

four chambered heart arises from cranial and caudal AV endocardial cushions
grow towards each other forming R and L AV canal

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4
Q

Where does the IV septum grow from and what does it unite with?

A

grows from the ventral floor to divide R and L ventricles uniting with the AV cushions via gelatinous membrane

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5
Q

Separation of the atria(2)

A

septum primum- descends in caudoventral direction and becomes flap for foramen ovale
septum secondum- develops thick partition, definitive septum

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6
Q

The aorta has

A

spiral septum which separates pulmonary trunk and aorta

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7
Q

What are the 4 distinct circulations that exist

A

Yolk sac vitelline circulation
Alantoic Umbilical circulation
Systemic circulation
Pulmonary circulation

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8
Q

Yolk sac vitelline circulation(2)

A

embryo to yolk sac -
omphalomeseteric artery
from yolk sac to heart-
omphalomesenteric vein

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9
Q

Allantoic/umbilical circulation

A

from heart ->allantois
*allantoic or umbilical artery
from allantois ->heart
*allantoic or umbilical vein

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10
Q

systemic circulation

A

heart->embryonic body
paired ventral and dorsal aorta
embryonic body->heart
*cardinal veins

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11
Q

Pulmonic circulation

A

most of the blood is shunted via the ductus arteriosus (6th arch) to aortic circulation

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12
Q

Aortic arches

A

all 6 are never present at one time

3,4,6 contribute to final vascular path

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13
Q

in the fetus, which side of the heart is doing more work

A

right

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14
Q

what capacity does the fetal heart work at?

A

full capacity

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15
Q

What type of resistance does the placenta have and what does it result in

A

placenta is low resistance so systemic arterial circulation is low resistance
while lungs are high resistance (collapsed)

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16
Q

Ductus venosus

A

wide venous channel in the liver that bypasses hepatic sinusoids (get O2 blood to heart)

17
Q

Foramen ovale

A

O2 blood diverted from RA to LA where it is preferentially delivered to heart and brain

18
Q

Ductus Arteriosus

A

large muscular artery connecting pulmonary trunk to aortic arch
diverts R to L(to aorta) ->placenta

19
Q

After birth sudden inc in pulmonary Blood flow->

A

inc venous return to L atrium

20
Q

loss of placenta->

A

sudden inc of systemic arterial resistance

21
Q

Closure of ductus venosus

A

passive closure hours/days after birth

22
Q

Remnant of foramen ovale forms

A

fossa ovalis of R atrium