Lecture 23C - Skin Infections Flashcards
What is the cause of acne vulgaris?
blockage of the psilosebaceous unit by propionium bacterium acnes can allow infection and formation of pustules
What are the symptoms of acne?
if the infection is severe and the hair follicle ruptures, scarring can ensue
What does colonisation of the blocked psilosebaceous unit cause?
formation of whiteheads, blackheads and pustules
Treatment of acne vulgaris?
depending on severity
topical benzoyl preoxide
tetracycline might be considered if symptoms are severe
What are the two most common bacteria causing skin infection?
staphylococcus aureus and streptococcus pyogenes
What are vesicles?
smaller fluid filled blisters the size of a pin head (<0.5m in diameter)
What are bullae?
larger fluid filled blister-like eruptions around 1cm (>0.5cm)
What is impetigo?
bacterial infection in the skin which commonly affects face or extremities following injury
What can form with impetigo?
bullae and/or vesicles can form, very contagious
Causative factors of impetigo?
usually caused by S aureus and S pyogenes
Symptoms of impetigo?
non-bullous type has pinhead pustules on red skin which erupt to give yellow-brown crust after skin injury (around 70% of cases)
Bullous type of impetigo?
has larger blisters which release a clear yellow liquid to leave a golden yellow crust (usually S aureus on intact skin)
Treatment of impetigo?
topical treatment with bacitracin or mupirocin
although resistance in some areas
care in playgroups to avoid spreading
often resolves spontaneously
What causes ecthyma?
often progresses from untreated impetigo
poor hygiene, poor ventilation of skin, insect bites, immunocompromised conditions
What is ecthyma commonly associated with?
S pyogenes and S aureus, however other bacterial species can be associated
Signs of ecthyma?
infection penetrates to deeper layers of the skin causing the appearance of painful ulcers
Treatment of ecthyma?
warm compress and antibiotics e.g. dicloxacillin
Folliculitis causes?
infection of hair follicles by S aureus
often affects beards, armpits and back of the neck
Symptoms of folliculitis?
red pustules (furuncles) form and eventually rupture in a few days
Treatment of folliculitis?
should be self limiting
topical clindamycin and erythromycin on affected areas if necessary and antibacterial soap
larger abscesses (carbuncles) may need to be surgically drained
Causes of erysipelas?
involved lymphatic vessels
often caused by S pyogenes and cellulitis by S aureus (inc. MRSA)
What can erysipelas cause?
systemic illness if untreated by passing through lymphatic vessels
Signs and symptoms of erysipelas and cellulitis?
pain ful, warm, red swelling which forms a well defined plaque
Treatment of erysipelas?
penicillin
Treatment of cellulitis?
dicloxacillin
What is erysipelas also known as?
St Anthony’s fire due to red borders round infection
What happens in cellulitis?
the infection has penetrated into subcutaneous tissue
Borders of cellulitis infection?
not well defined, much less than erysipelas
What can cellulitis lead to?
sepsis, requires antibiotic treatment and consideration of hospital admission
What is necrotizing fasciitis?
infection of subcutaneous tissue which can occur after surgery or trauma
What is necrotizing fasciitis caused by?
S pyogenes alone but often involves a mixture of bacteria
Symptoms of necrotizing fasciitis?
starts with war red skin but lesion rapidly expands vertically and horizontally
tissue becomes dark, pustular then necrotic *blackened areas where tissue as died) with gengrene
Treatment of nectrozing fasciitis?
fatal without prompt treatment
surgical intervention required along with parenteral antibiotics such as gentamicin and clindamycin