Lecture 22 Flashcards

Virulence, symptoms, and portals of exit

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1
Q

What is enterotoxin? Who produces it?

A

an exotoxin which affects the GI tract produced by staph aureus and e coli

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1
Q

a local infection which then spreads to other parts of the body

A

Focal infection

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2
Q

What are endotoxins?

A

non specific toxins releases when G- bacteria die

causes fever, shock, death

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2
Q

Why don’t you want to give an immunocompromised patient with a serioud G- infection a bunch of antibiotics?

A

all the bacteria will die pretty much at once and cause G- shock which can be deadly

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3
Q

Exaltation

A

increase the virulence of an organism by passing through lots of suceptible hosts (because of mutations and lysogenic conversion)

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4
Q

saprophytes growing on dead tissue of a living organism

A

Sapremia

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5
Q

Fungemia

A

having pathogenic fungi in your blood (systemic mycosis)

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5
Q

a decrease in virulence caused by increasing temperatures, chemicals, growth on lab media

A

Attenuation

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6
Q

Systemic

A

affects the entire body

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6
Q

a quick onset, infection will last a short amount of time

A

Acute

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6
Q

having pathogenic bacteria in your blood

A

Bacterenemia

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7
Q

Name some (5) portals of exit

A

feces

urine

sputum

secretions

blood

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8
Q

What is streptolysin and what does it do?

A

destroys red blood cells made by streptococci

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9
Q

Virunemia

A

having pathogenic viruses in your blood (HIV)

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9
Q

having pathogenic organisms in your blood

A

Septicemia

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11
Q

Acute

A

a quick onset, infection will last a short amount of time

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11
Q

What is hemolysin and what does it do?

A

a toxin that destroys red blood cells

can cause anemia or anoxia/hypnoxia (a decrease in the amount of oxygen to cells)

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11
Q

affects the entire body

A

Systemic

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13
Q

having pathogenic fungi in your blood (systemic mycosis)

A

Fungemia

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15
Q

organisms which are pus producing

A

Pyogenic

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17
Q

Pyemia

A

having pus producing organisms in your blood

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17
Q

any organism which can produce a toxin in the blood

A

Toxemia

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18
Q

Focal infection

A

a local infection which then spreads to other parts of the body

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18
Q

increase the virulence of an organism by passing through lots of suceptible hosts (because of mutations and lysogenic conversion)

A

Exaltation

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18
Q

qualitative, subjective

includes pain and nausea

A

Symptom

19
Q

Chronic

A

slow onset, infection lasts a long time

20
Q

slow onset, infection lasts a long time

A

Chronic

21
Q

Attenuation

A

a decrease in virulence caused by increasing temperatures, chemicals, growth on lab media

22
Q

What is leucocidan and what does it do? Who produces it?

A

destroys white blood cells

produced by pyogenic cocci such as staph and strep

24
Q

What are aggressins?

A

extracellular enzymes produced to increase invasiveness

25
Q

Toxogenicity

A

can and does the organism produce toxins that can damage cells

26
Q

invasiveness

A

ability of an organism to spread throughout your body

26
Q

Septicemia

A

having pathogenic organisms in your blood

28
Q

List the aggressins (6)

A

hyaluronidase

collagenase

lecithase

streptolysins

leucocidin

kinases

29
Q

pyrogen

A

an organism which induces fever

31
Q

Sign

A

quantitative

is objective

includes fever, swelling, paralysis

32
Q

Syndrome

A

any group of signs and symptoms used to define a disease

33
Q

having pus producing organisms in your blood

A

Pyemia

35
Q

can and does the organism produce toxins that can damage cells

A

Toxogenicity

37
Q

Name an organism which produces collagenase

A

clostridium perforinges- causes gas gangrene (the organism is anerobic and the conective tissues are not well vascularized so there is not much oxygen)

38
Q

Sapremia

A

saprophytes growing on dead tissue of a living organism

40
Q

What is lecthinase and what does it do?

A

breaks down lecthin (a type of phospholipid which is found in cell membranes)

allows for the organism to destroy cell membranes causing the cell to burst and die

41
Q

Toxemia

A

any organism which can produce a toxin in the blood

43
Q

What 2 factors is virulence dependent upon?

A

invasiveness and toxogenicity

44
Q

ability of an organism to spread throughout your body

A

invasiveness

45
Q

any group of signs and symptoms used to define a disease

A

Syndrome

46
Q

What is collagenase and what does it do?

A

it breaks down collagen (a connective tissue)

allows the organism to spread through the connective tissues

47
Q

Symptom

A

qualitative subjective includes pain and nausea

48
Q

Name some organisms which produce hyaluronidase

A

clostridium perforinges- causes gas gangrene

streptococcus pyogenes- causes nephrotizing fascitis (flesh eating disease)

49
Q

What is hyaluronidase and what does it do?

A

breaks down hyaluronic acid (which cements our cells together) this allows for the organism to move between cells and spread

50
Q

infection which is confined to one area

A

Local infection

51
Q

having pathogenic viruses in your blood (HIV)

A

Virunemia

52
Q

What is a super antigen?

A

something which makes lots of antibodies which have no disease to fight causes an allergic reaction, rash

53
Q

What exotoxin is produced by clostridium tetani? What is it toxic to?

A

tetanospasmin

it is a neurotoxin

54
Q

Bacterenemia

A

having pathogenic bacteria in your blood

56
Q

Pyogenic

A

organisms which are pus producing

57
Q

quantitative is objective includes fever, swelling, paralysis

A

Sign

58
Q

Local infection

A

infection which is confined to one area

59
Q

What is kinase and what does it do?

A

it digests fibrin (which is found in clots)

60
Q

an organism which induces fever

A

pyrogen

61
Q

What exotoxin is produced by streptococcus pyogenes? What is it toxic to?

A

erythogenic toxin- a hemotoxin