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Microbiology Exam 3 > Lecture 22 > Flashcards

Lecture 22 Flashcards

Virulence, symptoms, and portals of exit

1
Q

What is enterotoxin? Who produces it?

A

an exotoxin which affects the GI tract produced by staph aureus and e coli

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1
Q

a local infection which then spreads to other parts of the body

A

Focal infection

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2
Q

What are endotoxins?

A

non specific toxins releases when G- bacteria die

causes fever, shock, death

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2
Q

Why don’t you want to give an immunocompromised patient with a serioud G- infection a bunch of antibiotics?

A

all the bacteria will die pretty much at once and cause G- shock which can be deadly

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3
Q

Exaltation

A

increase the virulence of an organism by passing through lots of suceptible hosts (because of mutations and lysogenic conversion)

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4
Q

saprophytes growing on dead tissue of a living organism

A

Sapremia

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5
Q

Fungemia

A

having pathogenic fungi in your blood (systemic mycosis)

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5
Q

a decrease in virulence caused by increasing temperatures, chemicals, growth on lab media

A

Attenuation

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6
Q

Systemic

A

affects the entire body

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6
Q

a quick onset, infection will last a short amount of time

A

Acute

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6
Q

having pathogenic bacteria in your blood

A

Bacterenemia

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7
Q

Name some (5) portals of exit

A

feces

urine

sputum

secretions

blood

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8
Q

What is streptolysin and what does it do?

A

destroys red blood cells made by streptococci

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9
Q

Virunemia

A

having pathogenic viruses in your blood (HIV)

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9
Q

having pathogenic organisms in your blood

A

Septicemia

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11
Q

Acute

A

a quick onset, infection will last a short amount of time

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11
Q

What is hemolysin and what does it do?

A

a toxin that destroys red blood cells

can cause anemia or anoxia/hypnoxia (a decrease in the amount of oxygen to cells)

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11
Q

affects the entire body

A

Systemic

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13
Q

having pathogenic fungi in your blood (systemic mycosis)

A

Fungemia

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15
Q

organisms which are pus producing

A

Pyogenic

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17
Q

Pyemia

A

having pus producing organisms in your blood

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17
Q

any organism which can produce a toxin in the blood

A

Toxemia

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18
Q

Focal infection

A

a local infection which then spreads to other parts of the body

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18
Q

increase the virulence of an organism by passing through lots of suceptible hosts (because of mutations and lysogenic conversion)

A

Exaltation

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18
qualitative, subjective includes pain and nausea
Symptom
19
Chronic
slow onset, infection lasts a long time
20
slow onset, infection lasts a long time
Chronic
21
Attenuation
a decrease in virulence caused by increasing temperatures, chemicals, growth on lab media
22
What is leucocidan and what does it do? Who produces it?
destroys white blood cells produced by pyogenic cocci such as staph and strep
24
What are aggressins?
extracellular enzymes produced to increase invasiveness
25
Toxogenicity
can and does the organism produce toxins that can damage cells
26
invasiveness
ability of an organism to spread throughout your body
26
Septicemia
having pathogenic organisms in your blood
28
List the aggressins (6)
hyaluronidase collagenase lecithase streptolysins leucocidin kinases
29
pyrogen
an organism which induces fever
31
Sign
quantitative is objective includes fever, swelling, paralysis
32
Syndrome
any group of signs and symptoms used to define a disease
33
having pus producing organisms in your blood
Pyemia
35
can and does the organism produce toxins that can damage cells
Toxogenicity
37
Name an organism which produces collagenase
clostridium perforinges- causes gas gangrene (the organism is anerobic and the conective tissues are not well vascularized so there is not much oxygen)
38
Sapremia
saprophytes growing on dead tissue of a living organism
40
What is lecthinase and what does it do?
breaks down lecthin (a type of phospholipid which is found in cell membranes) allows for the organism to destroy cell membranes causing the cell to burst and die
41
Toxemia
any organism which can produce a toxin in the blood
43
What 2 factors is virulence dependent upon?
invasiveness and toxogenicity
44
ability of an organism to spread throughout your body
invasiveness
45
any group of signs and symptoms used to define a disease
Syndrome
46
What is collagenase and what does it do?
it breaks down collagen (a connective tissue) allows the organism to spread through the connective tissues
47
Symptom
qualitative subjective includes pain and nausea
48
Name some organisms which produce hyaluronidase
clostridium perforinges- causes gas gangrene streptococcus pyogenes- causes nephrotizing fascitis (flesh eating disease)
49
What is hyaluronidase and what does it do?
breaks down hyaluronic acid (which cements our cells together) this allows for the organism to move between cells and spread
50
infection which is confined to one area
Local infection
51
having pathogenic viruses in your blood (HIV)
Virunemia
52
What is a super antigen?
something which makes lots of antibodies which have no disease to fight causes an allergic reaction, rash
53
What exotoxin is produced by clostridium tetani? What is it toxic to?
tetanospasmin it is a neurotoxin
54
Bacterenemia
having pathogenic bacteria in your blood
56
Pyogenic
organisms which are pus producing
57
quantitative is objective includes fever, swelling, paralysis
Sign
58
Local infection
infection which is confined to one area
59
What is kinase and what does it do?
it digests fibrin (which is found in clots)
60
an organism which induces fever
pyrogen
61
What exotoxin is produced by streptococcus pyogenes? What is it toxic to?
erythogenic toxin- a hemotoxin

Microbiology Exam 3 (11 decks)

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