Lecture 2 ep transport Flashcards
whic of following isnt a smalle uncharge polar molecule h20 urea glucose CO2
Glucose-
tf hydrophobic moles and ions can cross the lipid bilayer
f only phobic molecule ions are imperm and need channels and carriers
Tf glycerol can cross the Lipid bilayer
T it is a small uncharged polar mol
Carrier Contain tyr group ser group tryptophan group
tyr group
Selectivity filter of Carrier contains a K ion selects one type of ion depends on charge and distance b/n groups 2 and 3
2 and 3
tf carrier is only assessible from 1 side
f from both side
Net flux of ion channels downhill requires nrg influenced only by conc.
downhill influenced by conc and change in e- potential
tf carriers dont require a conformation change
F
Carriers dont get saturated Jmax occurs at km Jmax occurs when you have saturation km occurs at 1/2 jmxas
3 and 4
movement in carriers is from
high to low conc net flux = 0 when conc are same
tf in carriers conf. change occurs after dissociation
f binding conc. change dissociation
active transport affinity are different conc are same on both side affinity are same 2 and 3
2 and 3
ex of active transport
p type atpase
tf na/k atpase and h/k atpase both transport k into cell
T
Ca atpase move Ca out move Ca in moves Ca out and H in
moves Ca out
Involved in active transport MDR1 CFTR
MDR1
ABC transporter doesn phos itself only involved in active transport example includes Na/k pump
doesnt phos itself
TF CFTR require ATP for moving CL
F Cl moves down conc gradient needs ATP to open pump
crenated cells made when red blood cell placed in hypertonic soln red blood cell placed in hypotonic soln red blood cell placed in isotonic soln
red blood cell placed in hypertonic soln
tf water moves from low to high osmotic pressure
T
