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GI1 > Gastric Secretion and pancreatic secretion lecture 4 and 5 > Flashcards

Gastric Secretion and pancreatic secretion lecture 4 and 5 Flashcards

1
Q

IF

A

B12 absorption in SI

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2
Q

TF HCL dissolves insol Ca and Na

A

F Ca and Fe

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3
Q

mucus forms paste with HCO3 prevents killing of stomach cells line stomach lumen wall all the above

A

all the above

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4
Q

tf stomach is an exocrin organ

A

t

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5
Q

which cells only exists in fundus and body parietal cell chief cell g cell

A

parietal cell

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6
Q

tf chief cell exist in all parts of stomach and make HCL and IF

A

F they make pepsinogen

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7
Q

tf hcl is made against a small conc gradient

A

F a huge

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8
Q

pepsinogen

A

made by stomach and cleaved to pepsin when sees HCL

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9
Q

tf pepsin breaks down proteins such as glyc

A

F breaks down aromatic AA

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10
Q

which cell stimulates Pareitla cells to make HCL

A

G cell by making gastrin

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11
Q

tf fundus and body make up the pyloric gland

A

F oxythic gland

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12
Q

pyloric gland

A

makes up antrum of stomach

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13
Q

exchanger on serosal side of Par cell Na/ K K/ H HCO3/Na

A

Na/ K

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14
Q

TF in the par cell H+ is made from metabolism of CO2 and H20

A

T

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15
Q

Describe the route of K+ in the parietal cell

A

exchange with Na on serosal side once n cell goes down conc gradient into lumen then flows back into par cell because H+ goes down its conc. gradient(they r exchanged)

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16
Q

in the parietal cell of stomach during production of HCL HCO3 accum on the serosal side HCO3 acum on the lumen side HCO3 andHCL cotransport to lumen side

A

HCO3 accum on the serosal side(cap)

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17
Q

tf production of HCL dilutes NACL

A

T

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18
Q

alkaline tide

A

stomach acidified and HCO3 in blood

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19
Q

HCL production—- the — concentration

A

dilute the NaCl

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20
Q

Which cell turns off HCL production in stomach

A

D cell

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21
Q

Enterchromatin cell

A

makes histamine

andstim Par cell

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22
Q

SM plexus

A

act by vagus and stimulates

G cell, enterchrom.cell and Par cell

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23
Q

interfering with Histamine will turn of HCL production in stomach

How?

A

block H2 receptor on par cell

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24
Q

interfring with which pump in the luminal side of stomach will stop HCL procution

H/K exchanger

HCO3/CL exchanger

Na/K exchanger

A

H/K exchanger

other two are on serosal side

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25
Q

tf D cell sense ph<2

A

T

turns of HCL formation

26
Q

tf in cephalic phase d cell turn off

A

F

happens in gastric phase when food comes in and binds H+ ions

raises the Ph–> d cell off

27
Q

in the gastric phase what hormone triggers g cells to make gastrin

A

Pepsin inc to yield AA and peptides

28
Q

h binds to food and is bufered

A

gastric phase

29
Q

intestinal phase is triggered when

A

food enters SI

30
Q

roles of secretin

trigger D cell to make somatostain

trigger liver to make HCO3

forms GIP

A

trigger D cell to make somatostain

31
Q

competitive inh of gastrin

32
Q

turns stomach activity off

33
Q

glucose binds to receptors in

A

SI and forms GIP during intestinal phase

34
Q

TF glucose tells pancreas to make insulin during gastric phase

A

F

during intestinl phase

35
Q

When small amt of fod is ungested

ph is high

ur in the gastric phase

vagal activity is stimulated

A

vagal activity is stimulated

36
Q

tf pnacreas only secretes enzyme

A

f enzyme and fluid

37
Q

pancreatitis

A

pancreas doesnt make fluid

38
Q

duodenal ulcer

A

too much HCL eating wall of SI

39
Q

TF Pancreas secrete HCL in it lumen and HCO3 in its serosal side

A

F

opp

oppp of stomach

they make bicarb and reabsorb H+

40
Q

how are pancreas nd sal. glands same

A

as solution passes down duct and HCO3 secreted with CL absorbed.

BOth soln are bicarb rich

41
Q

centroacinar cells

A

make bicarb and part of pancreas

42
Q

acinar cells

A

make enzyme in the pancreas

43
Q

CL pumps

A

transfer fluid in pancreas

44
Q

tf Bicarb production dilutes Na in pancreatic secretion

A

F

Cl diluted Na stays constant

45
Q

enteropepsidase

A

makes trypsin from trypsinogen

46
Q

Secretin

A

stim centroacinar cels and duct cells to makes bicarb

47
Q

tf secritin is made in the pancreas

A

F in the SI

48
Q

tf prox SI cells only make secretin

49
Q

what stimular creats secretin in SI

50
Q

what does CCK do

A

inh gastrin function and inc acinar cells pancreas

51
Q

bind receptors on pancreas to make HCO3

52
Q

which of the follwoing does CCK not triggers

stomach

pancreas

GB

liver

53
Q

interferance with gastrin

54
Q

tf secretin will cause pancreas to relase enzymes

55
Q

fatty meal

A

CCK inc

gb contract bile salt released

56
Q

Secretin and CCK

A

higher HCO3 production

57
Q

AA and HCL

A

higher HCO3 production

58
Q

which of following isnt function of CCk

gd contract

enzyme made and released from pancreas

interfere with gastrin function

bicarb secretion from pancrease

A

bicarb secretion from pancrease

59
Q

phospholipase

A

1,4 cleavage

60
Q

tf enteropepsidase cleaves elastase

A

F

trypsin does

61
Q

polarized pump cell on one side

A

pancreat acinar cells and ducts

GI1 (8 decks)

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