Gastric Secretion and pancreatic secretion lecture 4 and 5 Flashcards
IF
B12 absorption in SI
TF HCL dissolves insol Ca and Na
F Ca and Fe
mucus forms paste with HCO3 prevents killing of stomach cells line stomach lumen wall all the above
all the above
tf stomach is an exocrin organ
t
which cells only exists in fundus and body parietal cell chief cell g cell
parietal cell
tf chief cell exist in all parts of stomach and make HCL and IF
F they make pepsinogen
tf hcl is made against a small conc gradient
F a huge
pepsinogen
made by stomach and cleaved to pepsin when sees HCL
tf pepsin breaks down proteins such as glyc
F breaks down aromatic AA
which cell stimulates Pareitla cells to make HCL
G cell by making gastrin
tf fundus and body make up the pyloric gland
F oxythic gland
pyloric gland
makes up antrum of stomach
exchanger on serosal side of Par cell Na/ K K/ H HCO3/Na
Na/ K
TF in the par cell H+ is made from metabolism of CO2 and H20
T
Describe the route of K+ in the parietal cell
exchange with Na on serosal side once n cell goes down conc gradient into lumen then flows back into par cell because H+ goes down its conc. gradient(they r exchanged)
in the parietal cell of stomach during production of HCL HCO3 accum on the serosal side HCO3 acum on the lumen side HCO3 andHCL cotransport to lumen side
HCO3 accum on the serosal side(cap)
tf production of HCL dilutes NACL
T
alkaline tide
stomach acidified and HCO3 in blood
HCL production—- the — concentration
dilute the NaCl
Which cell turns off HCL production in stomach
D cell
Enterchromatin cell
makes histamine
andstim Par cell
SM plexus
act by vagus and stimulates
G cell, enterchrom.cell and Par cell
interfering with Histamine will turn of HCL production in stomach
How?
block H2 receptor on par cell
interfring with which pump in the luminal side of stomach will stop HCL procution
H/K exchanger
HCO3/CL exchanger
Na/K exchanger
H/K exchanger
other two are on serosal side