Lecture 2 - Cardiac Cycle Flashcards
What are the two phases of the cardiac cycle and what do they mean?
Systole - Contraction
Diastole - Relaxation
What are the different stages of the cardiac cycle?
Diastole 1 – Isovolumic Relaxation
Diastole 2 – Ventricular Filling
Systole 1 – Isovolumic Contraction
Systole 2 – Ventricular Ejection
What happens during Diastole 1 – Isovolumic Relaxation?
All valves shut
No change in ventricular volume
Minimal ventricular volume (end-systolic volume)
Relaxation of ventricles
Atrium fills with blood
Atria pressure increases until >ventricular pressure
What happens during diastole 2 - ventricular filling?
When atrial pressure> ventricular pressure AV opens passively
Ventricular filling
90% filling passive
Last 10% from atrial contraction
What happens during systole 1 - isovolumic contraction?
Ventricles filled
Ventricular depolarisation
Ventricle contracts
Ventricular pressure rises
AV valve closes so all valves shut
What happens during systole 2 - Ventricular Ejection?
ventricular pressure> aortic pressure
aortic valve opens
blood into aorta
What is the cardiac cycle?
The cardiac cycle is a series of mechanical events which associates temporally with electrical and valvular events.
What happens to ventricular volume during isovolumic relaxation?
Constant
What happens to ventricular volume during ventricular filling?
Rapid during early stages and slow during late stages (besides top up after atrial contraction). At this stage we have maximum ventricular volume (end of diastole volume – EDV).
What happens to ventricular volume during isometric contraction?
Constant
What happens to ventricular volume during ventricular ejection?
Decrease in volume, rapid in early stages, slower in later. At end of stage we have lowest ventricular blood volume (end-systole volume - ESV)
What happens to ventricular pressure during diastole?
Minimum at beginning but slight rise during ventricular filling and after atrial contraction.
What happens to ventricular pressure during systole?
Rapid rising during isometric contraction. Continues rising to maximum during ejection phase. Falls late systole to prepare for diastole.
What happens to arterial pressure during diastole?
Continues to fall until minimum
Minimum at end of diastole/during isovolumetric contraction
(Diastolic blood pressure)
What happens to arterial pressure during systole?
Rises to max
LVP > AP valves open
Rises to a maximum
(Systolic blood pressure)
LVP < AP valve closes
Why do we have the aortic notch/dicrotic notch/incisura?
Aortic valve closing
What happens when we miss 1-2 heart beats?
No problem
What happens when we miss 5-10 heart beats?
unconscious
What happens when we miss 5 mins of heart beats?
Clinical help - damaged heart
What happens when we miss >10mins of heart beats?
Death