lecture 2 - amino acids Flashcards
1
Q
glycine (3 letter)
A
gly
2
Q
glycine (1 letter)
A
G
3
Q
gly
A
glycine
4
Q
G
A
glycine
5
Q
alanine (3 letter)
A
ala
6
Q
alanine (1 letter)
A
A
7
Q
ala
A
alanine
8
Q
A
A
alanine
9
Q
proline (3 letter)
A
pro
10
Q
proline (1 letter)
A
P
11
Q
pro
A
proline
12
Q
P
A
proline
13
Q
valine (3 letter)
A
val
14
Q
valine (1 letter)
A
V
15
Q
val
A
valine
16
Q
V
A
valine
17
Q
leucine (3 letter)
A
leu
18
Q
leucine (1 letter)
A
L
19
Q
leu
A
leucine
20
Q
L
A
leucine
21
Q
isoleucine (3 letter)
A
ile
22
Q
isoleucine (1 letter)
A
I
23
Q
ile
A
isoleucine
24
Q
I
A
isoleucine
25
methionine (3 letter)
met
26
methionine (1 letter)
M
27
met
methionine
28
M
methionine
29
phenylalanine (3 letter)
phe
30
phenylalanine (1 letter)
F
31
phe
phenylalanine
32
F
phenylalanine
33
tyrosine (3 letter)
tyr
34
tyrosine (1 letter)
Y
35
tyr
tyrosine
36
Y
tyrosine
37
tryptophan (3 letter)
trp
38
tryptophan (1 letter)
W
39
trp
tryptophan
40
W
tryptophan
41
serine (3 letter)
ser
42
serine (1 letter)
S
43
ser
serine
44
S
serine
45
threonine (3 letter)
thr
46
theronine (1 letter)
T
47
thr
theronine
48
T
theronine
49
cystine (3 letter)
cys
50
cystine (1 letter)
C
51
Cys
cystine
52
C
cystine
53
asparagine (3 letter)
asn
54
asparagine (1 letter)
N
55
asn
asparagine
56
N
asparagine
57
glutamine (3 letter)
gln
58
glutamine (1 letter)
Q
59
gln
glutamine
60
Q
glutamine
61
lysine (3 letter)
lys
62
lysine (1 letter)
K
63
lys
lysine
64
K
lysine
65
histidine (3 letter)
his
66
histidine (1 letter)
H
67
his
histidine
68
H
histidine
69
arginine (3 letter)
arg
70
arginine (1 letter)
R
71
arg
arginine
72
R
arginine
73
asparate (3 letter)
asp
74
asparate (1 letter)
D
75
asp
asparate
76
D
asparate
77
glutamate (3 letter)
glu
78
glutamate (1 letter)
E
79
glu
glutamate
80
E
glutamate
81
non-polar, aliphatic
glycine, alanine, proline, valine, leucine, isoleucine, methionine
-glycine =predominantly in zwitterion (nh3 = +, coo = -)
82
polar, uncharged
serine, threonine, cystine, asparagine, glutamine
| -can form Hbonds, both donors and acceptors
83
aromatic
phenylalanine, tyrosine, tryptophan
| -tyr and trp have some hbonding ability
84
positively charged
lysine, arginine, histidine
- lys & arg = predominantly positively charged
- his can be pos or neutral (pkr=6), at ph=7 = 9% pos (protonated) and 91% neutral (deprotonated)
85
negatively charged
asparate, glutamate
| -both predominantly negatively charged
86
isoelectric point:
pH where net charge = 0
87
pH < pI
positive charge bc excess protons in solution
88
pH > pI
negative charge because protonated
89
pH = pI
neutral
90
at pH = pKa
equal amounts of protonated and deprotonated
91
at pH = pKa + 1
91% deprotonated
92
at pH = pKa - 1
91% protonated
