Lecture 2 Flashcards

1
Q

What is a palpable lesion

A

Is a sweling that is not seen but felt

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2
Q

In histology what is the difference between situ and invasive

A

In situ the cells have not crossed the basement membrane while invasive the cells cross the basement membrane and goes to the nearest organ

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3
Q

When is catheterized urine collected

A

In situations when someone is unable to hold urine e.g indweling catheter

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4
Q

What are the disadvantages of indweling catheter

A
  1. The cells may damage or deteriorate due to overstay in the catheter
  2. Cells disloged by catheter can mimic abnormal cells
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5
Q

Define bladder washing

A

Is the use of catheter as a passage to flush the bladder with normal seline (0.85 -0.95 Naoh)

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6
Q

Why do we use normal saline in various lab test

A

Because the concentration of normal saline is similar to that of bodily salts as a result the cells are not damaged

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7
Q

Explain the technique of bladder washing

A

A sringe will pump normal saline into the catheter to the bladder and pumped back into the sringe and it is used immediately

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8
Q

What are the fluids that are used in histology

A
  1. Pleural fluid
  2. Csf fluid
  3. Bronchoaveoli. Secretions between bronchi and alveoli/ flushing normal saline in the airways
  4. Sputum
  5. Servical smear and vaginal smear
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9
Q

What is cytocentrifugation

A

Cytocentrifugation, also known as a cytospin, is a specialized laboratory technique used to concentrate cells from fluid specimens onto a microscope slide.

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10
Q

What causes cervical cancer

A

HPV virus

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11
Q

Mode of transmission of HPV virus

A

Sexually transmitted

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12
Q

What is genital warts

A

Genital warts, also known as condylomata acuminata, are soft growths that appear on or around the genitals. Here’s what you need to know:
Cause and Transmission:
Genital warts are caused by the human papillomavirus (HPV).
There are more than 40 strains of HPV that affect the genital area.
These warts are spread through sexual contact. Even if they are too small to be seen, you can still transmit the infection to your sexual partner.
Appearance and Symptoms:
Genital warts can grow on various parts of the genital area, including:
Vulva
Walls of the vagina
Area between the outer part of the genitals and the anus
Anal canal
Cervix
Tip or shaft of the penis
Scrotum
Anus
They can also form in the mouth or throat of a person who has had oral sex with an infected individual.
Symptoms include:
Small swellings in the genital area (which may be skin-colored or a different color).
A cauliflower-like shape caused by several warts close together.
Itching or discomfort in the genital area.
Bleeding during sex.
Sometimes, genital warts can be so small and flat that they are not visible to the naked eye. However, in individuals with weakened immune systems, they can multiply into large clusters.
Risk Factors:
Most sexually active people get infected with genital HPV at some point.
Factors that raise the risk of infection include:
Not getting the HPV vaccine
Unprotected sex (without a condom) or having multiple sexual partners
History of other sexually transmitted infections
Sexual partners with unknown sexual history
Early sexual activity
Weakened immune system (e.g., due to HIV or organ transplant medications)

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13
Q

What is hpv 6

A

HPV 6 is one of the low-risk types of the human papillomavirus (HPV). Let’s explore more about it:
Characteristics:
HPV 6 is associated with approximately 90% of genital warts.
It can also cause changes to the cervix.
Genital warts appear as cauliflower-shaped bumps on the genitalia and usually manifest a few weeks or months after exposure to a sexual partner who has HPV.
These warts are considered low-risk because they do not lead to cancer or other serious health problems.

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14
Q

Explain the pathogenis of hpv

A

After infection it will affecting the bassal aquamous tissue then it will go to parabasal then intermediate cells

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15
Q

What is the transformation zone

A

Is important in the cervical cancer screening because it is where cancer beggins

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16
Q

When canwe do Pap smear

A

12 days after menstruction period

17
Q

What materials are needed to do Pap smear specimen collection

A

Gynaecologic bed
Speculum
Gloves
Normal saline
Collection devices

18
Q

What are the types of urine specimens used for cytologic purposes

A
  1. Voided urine (clean catch is recommended)
  2. Catheterized urine
  3. Bladder washing
19
Q

What are the advantages of fine needle aspiration

A

1.Any organ can be reached with this technique
2. Several passes are made through the mass

20
Q

What is fine needle aspiration

A

Is a means of obtaining a specimen from superficial or deep seated masses using fine needles

21
Q

Explain the procedure of fine needle aspiration

A

A syringe is attached to the needle for aspiration to contain potential fluid from the mass
Fixation is done immediately after smear preparation( 15 sec delày leads to air dry)
Leave smear in fixative for atleast 15 min to air dry
Stain and mount ready for microscope examination

22
Q

What is a cervix

A

Is aan opening of the uterine cavity into vagina

23
Q

Differentiate endocervix and ectocervix

A

Indocervix is inside while ectocervix is outside

Ectocervix is made up of non-keratinising squamous cell epithelim while endocervix is made up of collumnar epithelium

24
Q

What is the transfomartion zone

A

Is the area where two epithelial meet
It is where cancer arises from

25
Q

What should a pap smear contain

A

Squamous and collumnar epithelial cells

26
Q

Mention the 3 regions of a squamous epithelial cell

A
  1. Basal layer (bottom region)
  2. Intermediate layer (Middle region)
  3. Superficial layer (outer most layer)
27
Q

Outline the summary of procedure for cervical smear collection

A
  1. Secure a private place
  2. Assemble the matterials
  3. Explain the procedure to the client and obtain consent
  4. Put on examination gloves
  5. Position the patient to the edge of the exam table
  6. Inspect the vulva
  7. Separate the labia and gently insert the speculum
  8. Ensure the entire cervix is in gull view
  9. Use a spatula to sample the ectocervix and use the brush to sample the endocervical canal
  10. Remove the speculum
  11. Spread the soecimen on a glass slide and make a thin preparation possible
  12. Fix the smear immediately to avoid air drying
  13. Wait 15 mins before staining