Lecture 19-20 Flashcards
Diffuse Placenta
Horses and Pigs
Cotyledonary
Ruminants (cattle, goats, sheep, deer)
Zonary
Carnivores (dogs, cats, ferret)
Discoid
Humans, apes, monkeys, rodents
Epitheliochorial
pigs, horse, ruminants
least intimate exchange
young born leaner, lower nutrients, and less immunity
endotheliochorial
dogs, cats
hemochorial
humans,rodents
Most intimate exhange between mom and fetus
young have higher fat and nutrient stores
more developed immune system
Ruminant epitheliochorial
Syndesmochorial: the endometrial epithelium transiently erodes and then regrows so maternal connective tissues are intermittently exposed to the chorionic epithelium
Made up of Bi-nucleate cells
Binucleate Giant Cells
–migrate from chorionic to endomet. epithelium
–transfer complex mlcls from fetus to mom
–endocrine fxn (secretes lactogen, steroid and PAG’s)
–constitutes 20% of fetal placenta
–originated from trophoblast cells
Placental Function
The placenta is a transient organ: metabolic interchange between mother and fetus
the placenta is is the major endocrine organ of preg: produces hormones, stims mammary glands, and promotes fetal growth
Maternal-Fetal Exhange mechanisms
Simple Diffusion: High [ ] to low [ ] (gas and water)
Facilitated: membrane transport (proteins and glucose)
Active Transport: membrane proteins transport AGAINST gradient (Na, K, and Ca ++)
Can Cross and Can’t
pg 8 and 9 of Lec. 19
Placental Hormones Can . .
Stim Ovarian Fxn
Maintain Pregnancy
Influence Fetal Growth
Stim Mammary Function
Assist in Parturition
Progesterone
CL produces most P4 at first and then placenta
CL: secretion of endometrial glands and embryonic membrane attachment
Placenta: maintains preg
depends on species if this takes over
Progesterone Block
High P4 blocks myometrial contractions
ecg = PMSG
produced by endometrial cups of placenta
5-10 develop over placental surface
develop between days 35-60 and slough around 100
-Maintains primary CL
-forms and maintains supplemnetary CL’s
-acts like FSH
hCG
primates
from trophoblastic cells
found in blood and urine after 8-10 days of preg
pg 12 lec 19