Lecture 17 - Skeletal Muscle Flashcards

1
Q

How do we generate the force to produce movement?

A

Skeletal muscle

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2
Q

What are the properties of muscle tissue?

A

Excitability, conducts electrical impulses, contractibility, extensibility, elasticity

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3
Q

What is excitability?

A

The property of muscle being sensitive or responsive to chemical, electrical, or mechanical stimuli

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4
Q

What is contractibility?

A

The ability of muscle to contract and develop tension or internal force against resistance when stimulated

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5
Q

What is extensibility?

A

The ability of muscle to be stretched back to its original length following contraction

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6
Q

What is elasticity?

A

The ability of muscle to return to it’s original length following stretching

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7
Q

What are agonist muscles?

A

Muscles that cause joint motion through a specified plane of motion when contracting concentrically

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8
Q

What are agonist muscles also known as?

A

Primary/prime movers

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9
Q

What are antagonist muscles?

A

Muscles located on the opposite side of a joint from an agonist that contract concentrically to perform the opposite joint motion of agonist muscles

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10
Q

What are agonist muscles also known as?

A

Contralateral muscles

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11
Q

What are synergist muscles?

A

Muscles that assist in action of agonists that assist in refined movement and reduce undesired motions

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12
Q

What are synergist muscles also known as?

A

Guiding muscles

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13
Q

What is the epimysium?

A

Connective tissue surrounding the entire muscle

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14
Q

What is the perimysium?

A

Connective tissue surrounding the bundles of muscle fibers (fascicles)

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15
Q

What is the endomysium?

A

Connective tissue surrounding individual muscle fibers

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16
Q

What is the sarcolemma?

A

The muscle cell membrane

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17
Q

What are myofibrils?

A

Threadlike strands within muscle fibers made up of actin and myosin

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18
Q

What is actin?

A

Thin filament made up of troponin and tropomyosin

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19
Q

What is myosin?

A

Thick filament

20
Q

What is a sarcomere?

A

The smallest contractile unit of skeletal muscle

21
Q

What is a motor unit?

A

A single motor neuron and muscle fibers it innervates

22
Q

Why does the CNS alternate the motor units it recruits?

A

To reduce fatigue and distribute work load

23
Q

What are the types of muscle contractions?

A

Isometric and isotonic

24
Q

What is an isometric contraction?

A

A contraction where the muscle exerts force without changing length

25
Q

What is an isotonic contraction?

A

A contraction where the muscle exerts force by changing length

26
Q

What are the types of isotonic contraction?

A

Concentric and eccentric

27
Q

What is a concentric contraction?

A

A contraction where the muscle shortens during force production

28
Q

What is an eccentric contraction?

A

A contraction where the muscle length increases during force production

29
Q

How does neural excitation move to muscle force?

A

Muscle activation dynamics (excitation contraction coupling) and muscle contraction dynamics

30
Q

What is force output dependent on?

A

Muscle length, velocity, and activation of the muscle unit

31
Q

Who is A.V. Hill?

A

Physiologist who studies the chemical and mechanical properties of muscle

32
Q

What did A.V Hill conclude in his first experiment?

A

Multiple motor units combine to produce a usable force that can be increased by the nervous system by recruiting more motor units or increasing the frequency of action potentials

33
Q

What did A.V. Hill observe about muscle mechanics in his first experiment?

A

That contraction begins with the twitch of a muscle fiber

34
Q

What is a twitch?

A

A force produced by an isometric muscle response to an action potential in one or more motor units

35
Q

What is the summation of twitches?

A

When the muscle is not allowed to relax between action potentials to the point of tetanus?

36
Q

When does tetanus occur in humans?

A

50-60 Hz

37
Q

What was A.V. Hill’s second experiment?

A

Force Length

38
Q

How did A.V. Hill observe force length?

A

By measuring passive and active force

39
Q

What did A.V. Hill observe about active length tension in his second experiment?

A

Active length tension relationships are directly related to sarcomere length

40
Q

What happens when a sarcomere is too long?

A

It is unable to crossbridge

41
Q

What happens when a sarcomere is too short?

A

It is unable to contract further because thin filaments hit each other

42
Q

What did A.V. Hill observe about passive length tension in his second experiment?

A

Passive length tension is like a spring (non linear) due to connective tissue

43
Q

What did A.V. Hill observe about muscles during unloading vs loading in his second experiment.

A

Hyesteresis, different length tension properties apply when loading and unloading tissue

44
Q

Can active and passive tension be combined to produce force?

A

Yes

45
Q

What was A.V Hill’s third experiment?

A

Force velocity relationship