Lecture 16: Performing Enhancing Drugs Flashcards
What is used for the treatment of ADHD?
Methylphenidate
What is used for narcolepsy?
Modafinil
What is the constitute of cigarettes?
Nicotine
What does nicotine affect?
The cholinergic system
What is nicotine?
ACH agonist
What does nicotine stimulate?
ACH receptors which are ionotropic receptors
What can the administration of nicotine improve?
Performance
Who are more sensitive to the effects of nicotine?
Smokers
Is the mean reaction time quicker or slower for smokers or non smokers
Smokers
In what terms does nicotine have a cognitive enhancing function?
Visual information processing Reaction time
Where was the performance study done?
Radical arm maze
What is the radial arm maze?
Set of runways that all radiate out from the central point
In term of the radial arm maze, what is found to be an improved cognitive performance?
Making less repeated arm entries
What does the administration of nicotine allow animal to do?
Remember where it has been > improved cognitive performance (spatial working memory)
In a specific region of the brain there is a confirmation of nicotinic ACH receptors, what are they referred to as?
Alpha-beta composition
Where does nicotine have an effect upon?
Hippocampus (spatial memory)
What happens when nicotine stimulates receptors within hippocampus and other brain regions?
Bring positive modulatory effects in terms of how the animal performs on anything that depends on its spatial awareness and spatial memory
In how many modalities does nicotine have cognitive enhancing abilities?
One