Lecture 16 & 17 Flashcards
Transport of oxygenated blood
Arteries
Act as valves for entry into capillaries
Arterioles
Gas and nutrient exchange
Capillaries
Collects blood from capillary
Venules
Carry deoxygenated blood back to heart
Veins
- Contains lining of simple squamous epithelium (endothelium), basement membrane, and layer of elastic tissue (internal elastic lamina)
- Endothelium lines entire cardiovascular system and is only tissue that contacts blood
Tunica interna (intima)
- Thickest layer, middle layer
- Consists of elastic fibers and smooth muscle that extend circularly around the lumen
Tunica media
- Outermost layer
- Composed mainly of elastic and collagen fibers
- In muscular arteries, an external elastic lamina composed of elastic tissue separates the tunica externa form the tunica media
Tunica externa
Type of artery with largest diameter - tunica media contains large amounts of elastic fibers
Elastic arteries
This type of artery has
- More smooth muscle in tunica media (which is innervated by SNS)
- Fewer elastic fibers
- Capable of greater vasoconstriction and vasodilation to adjust blood flow
Muscular arteries
Carry oxygenated blood and empties into capillaries
Arterioles
Control blood flow into capillary bed
Metarterioles and precapillary sphincters
Site of gas and fluid exchange with the tissues
Capillaries
The wall of this is very thin (good for gas exchange); consists of a layer of endothelium and underlying basement membrane. They do not contain smooth muscle thus they are not capable of vasoconstriction or vasodilation
Capillaries
Receive deoxygenated blood from capillaries
Venules
Have smooth muscle, and are capable of vasoconstriction and vasodilation
Arterioles and venules
Consist of same three tunics as arteries (tunica interna, tunica media, tunica externa)
Veins
Much more compliant than arteries - can hold more blood, so they act as a reservoir.
Veins
Contain valves that prevent backflow of blood
Veins
The force exerted on the walls of the blood vessels by the blood
Blood Pressure
Blood flows through the body due to _______
Pressure gradient
Mean Arterial Pressure (MAP) equation
MAP=DBP + 1/3 (SBP-DBP)
_____ Represents the pressure gradient in the systemic circulation and is the major driving force for blood flow through the systemic circulation.
MAP (Mean Arterial Pressure)
Is pressure gradient in pulmonary circulation high or low?
Low
Is pressure gradient in systemic circulation high or low?
High
Pulse pressure equation
SBP-DBP
Factors that affect pulse pressure
Stroke volume and Compliance
Greater _____ results in greater pressure rise with each heart beat
Stroke volume
Lower _______ of artery results in a greater pressure rise with every beat
Compliance
________ are dampened further down the vascular tree; arterioles and capillaries do not experience significant _______
Pulsations (both blanks)
Factors that affect MAP
MAP = CO x TPR
______ is the resistance to blood flow through all of the vasculature in the body.
TPR