Lecture 15: Ear Development Flashcards
When is the critical period for embryological development of the ear?
Weeks 4-8
When does development of the ear occur?
Week 4-20
What is found in the external, middle, and inner ear?
External Ear
- Auricle
- External Acoustic Meatus
- External Layer of Tympanic Membrane
Middle Ear
- Auditory Ossicles (3)
- Internal Layer of Tympanic Membrane
- Middle Ear Cavity
Inner Ear
- Vestibulocochlear Organ
- Develops separately from external and internal ear
The medial part of the external ear came from what pharyngeal arch?
1st Pharyngeal Arch
The lateral part of the external ear came from what pharyngeal arch?
2nd Pharyngeal Arch
The mesenchymal swellings located within the pharyngeal arches are known as what?
Auricular Hillocks
What are the cells that migrate and pull the surface ectoderm around to form the external ear?
Neural crest cells of the auricular hillocks
Auricular skin tags that may contain cartilage are a result of what?
Abnormal migration of surface ectoderm and neural crest cells
Abnormal or absent migration of the NCCs and auricular hillocks can result in what disorders?
Anotia
Microtia
What embryonic layer does the meatal plug arise from?
Surface ectoderm
1st Pharyngeal Cleft
What embryonic layer forms the tubotympanic recess?
Endoderm: 1st Pharyngeal Pouch
What embryonic layer does the inner ear arise from?
Surface ectoderm
How does the inner ear form from surface ectoderm?
- Otic Placode thickens
- Invaginates to form Otic Pit
- Becomes Otic Vesicle that migrates to the head
What embryonic structure gives rise to the membranous labyrinth?
Otic vesicle
Also Surface Ectoderm
What does the dorsal side of the otocyst give rise to?
Utricle
- Endolymphatic duct and sac
- Semicircular ducts and ampullae
- Macula of utricle