lecture 15 Flashcards

1
Q

digestion in the mouth

A

salivary alpha-amylase hydrolyzes alpha-1,4 glycosidic bonds in amylose and amylopectin, forming dextrins

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2
Q

digestion in the stomach

A

no digestin of amylose and amylopectin, dextrins pass unchanged

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3
Q

digestion in the small intestine (pancreas)

A

pancreas releases pancreatic alpha-amylase into the samll intestine which hydrolyzes alpha-1,4 glycosidic bonds. dextrins are broken down into maltose and limit dextrins

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4
Q

digestion of amylose on the brush border

A

maltose is hydrolyzed by maltase, a brush border enzyme, forming free glucose

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5
Q

digestion of amylopectin on the brush border

A

maltose is hydrolyzed by maltase, a bursh border enzyme, forming free glucose. the alpha 1-6 glycosidic bonds in limit dextrins are hydrolyzed by alpha-dextrinase, forming glucose

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6
Q

what breaks down sucrose

A

sucrase

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7
Q

what breaks down maltose

A

maltase

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8
Q

what breaks down isomaltose

A

isomaltase

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9
Q

what breaks down dextrins

A

glucoamylase

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10
Q

what kind of bonds doese maltose break down

A

alpha 1-4

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11
Q

what kind of bonds does isomaltose break donw

A

alpha 1-6

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12
Q

where does lactose go in ppl with lactose intolerance

A

large intestine where microorganisms can metabolize it

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13
Q

what hydrolyzes lactose

A

lactase

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14
Q

why does lactose intolerance cause gas production

A

colonic bacteria ferment the undigested lactose, breaking it down into acids and gases.

his fermentation process produces various gases, including hydrogen, carbon dioxide, and methane.

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15
Q

active sugar transporter

A

SGLT1

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16
Q

what kind of pump is SGLT1

A

Na/K-ATPase

17
Q

facilitated sugar transporters

A

diffusion
GLUT2 (glucose and galactose)
GLUT5 (fructose)

18
Q

glut2 sugars

A

glucose and galactose

19
Q

glut5 sugar

20
Q

sglt1 sugars

A

glucose and galactose

21
Q

Na and K are both transported across the membrane ______ their concentration gradient

22
Q

the activity of what pump is the major energy demand of the body at resta nd is responsible for most of the active transport in the body

23
Q

SGLT1 _________ by the breakdown of _______ is able to move ____ Na out of enterocytes

A

phosphorylated, ATP, 3

24
Q

SGLT1 _______ by _______, brings back ___ K into the cell

A

dephosphorylated, hydrolysis, 2

25
what tissues is SGLT1 mainly expressed in
intestine, heart, kidney
26
what tissues is SGLT2 mainly expressed in
kidney
27
what tissues is SGLT3 mainly expressed in
intestine, spleen, liver, kidney, muscle
28
what transporters contribute to renal glucose reabsorption (glucosuria/dm)
SGLT1 and SGLT2
29
soluble/viscous fibers
pectin beta glucan (oats) hemi-cellulose
30
insoluble/non viscous fibers
cellulose lignin